In this highly requested AMA, Dr. Gabrielle Lyon addresses the most critical questions surrounding male hormone health. Dr. Lyon tackles the fear, stigma, and misinformation surrounding Testosterone Replacement Therapy (TRT), revealing why a low testosterone level is a major predictor of serious health issues like heart disease, bone fracture, and obesity.

She breaks down the current medical consensus on TRT, the risks of replacement, the truth about dosing, and what every man over 40 needs to know about their hormone health. This is a must-watch to separate the bodybuilding myths from the medical facts.

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In this powerful episode, Dr. Gabrielle Lyon sits down with legendary sales expert and entrepreneur Jeremy Miner to discuss the foundation of success. Jeremy, the founder of Seventh Level, reveals the mental frameworks, communication skills, and commitment required to achieve peak performance in any area of life.

Drawing from his own harrowing health scare and decades of experience coaching top performers, Jeremy shares candid insights into what separates the top 1% from everyone else. This conversation is not just about sales—it’s about the psychology of human connection, overcoming fear, and unlocking your full potential to build a mo...

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When you hear the word “radiation,” do you think of cancer, Chernobyl, or an airport scanner? In this powerful episode, Dr. Gabrielle Lyon sits down with Dr. Sanjay Mehta, a radiation oncologist, to completely redefine your understanding of radiation as a tool for medicine.

Dr. Mehta reveals how modern technology has...

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In this episode, Dr. Gabrielle Lyon sits down with pediatrician Dr. Joel Gator Warsh to confront the most concerning trends in children's health. Dr. Warsh, author of A Shot and a Hard Place, reveals the staggering rise of chronic disease and autism in children, arguing that it's a crisis that...

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In this episode, Dr. Gabrielle Lyon sits down with Dr. Teo Soleymani, a fellowship-trained skin cancer surgeon and dermatologist, to cut through the noise of the skincare industry. They discuss everything from viral trends like "glass skin" to the science behind hormones, sun protection, and the lifestyle factors that truly determine your skin's health and longevity.

Dr. Teo Soleymani debunks common myths and provides actionable, no-nonsense advice on what to use—and what to avoid—to buil...

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In this powerful episode, Dr. Gabrielle Lyon sits down with former Navy SEAL Commander and author, Rich Diviney, to break down what it takes to thrive under extreme pressure. Rich, author of "The Attributes and Mastering Uncertainty", reveals the psychology of elite performance, explaining why true toughness has less to do with physical strength and more to do with your mental attributes.

He shares candid insights into the realities of SEAL training, the mental tools used...

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In this episode, I sit down with nutritional physiologist and friend Nick Barringer, PhD, to tackle a crucial, yet often misunderstood, topic: women's hormonal health. We expose the devastating impact of the Women's Health Initiative study and why millions of women are left untreated for menopause symptoms, leading to an increased risk of issues like osteoporosis and Alzheimer's.

This is a no-nonsense guide for every woman, regardless of age, who wants to understand her hormones and...

In this compilation, Dr. Gabrielle Lyon brings together the top minds in health and fitness to deliver the ultimate guide to fat loss. Featuring the best moments with Dr. Mike Israetel, Dr. Layne Norton, and Don Saladino, this video cuts through the confusion and gives you a no-nonsense, science-backed approach to transforming your body.

You’ll hear from the experts on everything from the flawed science of calories to the truth about muscle, metabolism, and modern weight loss drugs like Ozempic. This is not about fads or quick fixes—it’s a masterclass in building a sustainable, health...

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We have all heard the sayings and clichés, but what is the truth behind being afraid of dying? In this episode, Dr. Gabrielle Lyon sits down with Elena Brower, a best-selling author, meditation teacher, and hospice volunteer, to discuss the profound topics of impermanence, living intentionally, and preparing for the end of life.

Drawing from her own experience with the loss of her mother, Elena shares her journey into hospice work and Buddhist chaplaincy, revealing how e...

In a powerful episode of the Dr. Gabrielle Lyon show, I sit down with my mentor, Dr. Donald Layman, to directly address some of the most common protein myths. We react to a controversial clip from the Huberman Lab podcast with Dr. Christopher Gardner, offering a different perspective on the conversation about protein intake, metabolic science, and dietary guidelines.

Dr. Layman, a pioneer in protein research, breaks down the outdated science behind the Recommended Dietary Allowance (RDA), the flaws of nitrogen balance studies, and why a protein-conscious approach is crucial for your long-term health, not just for...

In this groundbreaking episode, Dr. Gabrielle Lyon sits down with Dr. Tobias Kohler, a professor of urology at the Mayo Clinic, to discuss a topic most people are afraid to talk about: men's sexual health.

Dr. Kohler shares eye-opening insights, backed by over two decades of clinical experience and research, on the powerful link between foundational health habits and male sexual function. They reveal why erectile dysfunction is a critical "check engine light" for heart disease and how building muscle and exercising can improve not just your erections, but your overall longevity.

This conversation goes...

Are you struggling to get a good night's rest?

Do you think you can thrive on just a few hours of sleep? In this eye-opening episode, Dr. Gabrielle Lyon sits down with renowned sleep scientist Dr. Rebecca Robbins to debunk the biggest sleep myths and reveal the profound connection between sleep and your health, longevity, and daily performance. They dive into the science of sleep, from the homeostatic sleep drive to the crucial role of your circadian rhythm. You’ll learn why sleep isn't just a passive state for your brain and discover the shocking truth about "so...

Mysterious symptoms. Confusing diagnoses. Years of being dismissed.

In this episode, Michelle Shapiro joins me to unpack the often misunderstood and overlooked world of mast cell activation syndrome (MCAS), histamine intolerance, postural orthostatic tachycardia syndrome (POTS), and hypermobility conditions.

Drawing from her own health journey and experience with thousands of clients, Michelle unpacks why conventional medicine often overlooks these complex, overlapping conditions—and how a root-cause, systems-based approach can lead to real healing. From nervous system regulation to low-histamine nutrition, this episode is a must-listen for anyone struggling with unexplained chronic symptoms.

You’ll l...

Heart disease is the leading cause of death for women—yet it's still treated like a man’s disease. In this powerful conversation, Dr. Martha Gulati, a cardiologist and pioneer in women’s cardiovascular health, exposes the systemic gaps that leave women underdiagnosed, undertreated, and often unheard. Together, we unpack the critical differences in how heart disease presents in women, why standard diagnostic tools fall short, and what every woman needs to know about risk factors like pregnancy complications, hormone therapy, statin use, and even environmental exposures. Dr. Gulati also reveals the truth behind hormone therapy myths, explains how soft p...

Muscle health isn’t just about how much protein you eat—it’s about how your body uses it. And for people with obesity or advancing age, that process can become less effective, even with optimal nutrition.

In this episode, I am joined by Dr. Nick Burd, one of the world’s leading researchers in muscle metabolism, to unpack the concept of anabolic resistance—when muscle doesn’t respond normally to protein and/or exercise. Together, we explore how aging, obesity and even the way foods are combined on your plate can impact muscle remodeling, recovery, and growth. Dr...

Did you know every 40 seconds someone in the U.S. has a heart attack—and 1 in 5 never even see it coming? This week, I am joined by preventive cardiologist Dr. Michael Twyman as we discuss cutting-edge diagnostics, the endothelial glycocalyx, nitric oxide biology, and why muscle mass is your heart’s best friend. Learn the practical steps and questions to ask to protect your heart before symptoms appear.

Together, we explore:

In this episode, I’m joined by journalist and author Michael Joseph Gross, whose book, Stronger: The Untold Story of Muscle in Our Lives, reveals the powerful and often overlooked role of muscle in human health and society—tracing its importance from ancient civilizations to modern science. We explore how our understanding of muscle has evolved through history, from symbols of strength and vitality in antiquity to current misconceptions in modern society. Michael shares insights from his extensive research, highlighting the incredible resilience of muscle tissue, debunking common myths about strength and aging, and providing compelling evidence for why ever...

In this episode, Dr. Alexis Wood, a leading researcher at Baylor College of Medicine, joins me to unpack insights into childhood nutrition, genetics, and cognitive health. Dr. Wood's work bridges genetics, dietary practices, and brain development, highlighting how early-life nutrition can shape lifelong outcomes. We explore cutting-edge research, practical strategies for parents, and the surprising factors influencing children's cognitive and metabolic health.

We cover:

In this episode, I sit down with Dr. David Klurfeld—longtime USDA scientist and one of the few insiders to publicly challenge the WHO's classification of red meat as a carcinogen. We go deep into the flawed evidence behind the infamous 2015 IARC report, why nutritional epidemiology often fails to prove causality, and how a small group of researchers helped shape global policy with low-quality science. If you've ever felt confused about meat, saturated fat, or dietary guidelines, this conversation will help you think critically about what “counts” as evidence—and who gets to decide.

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Dr. Larry Lipshultz. is one of the world's leading experts in men's reproductive health. In this week's episode, we discuss testosterone therapy, male fertility, and the hidden environmental factors threatening men’s health. Dr. Lipshultz shares groundbreaking insights into why male fertility is declining, common myths surrounding testosterone and prostate cancer, and innovative strategies to safely enhance men's reproductive and overall health.

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What if your biggest challenge isn’t motivation but missing structure? In this episode, I sit down with Brian Johnson to unpack the science and philosophy of lasting behavior change. We explore the power of ancient wisdom, stoicism, and the neuroscience of excellence, and why most wellness apps fail to deliver real transformation.

Brian shares his personal journey from startup success to creating a global movement around character, discipline, and identity-based habits. We talk about the science of anti-fragility, how muscle mirrors virtue, and why the gap between who you are and who you could be is th...

When it comes to performance, more isn’t always better. In this episode, I sit down with conditioning expert Joel Jamieson to explore the science of recovery, aerobic fitness, and how to use heart rate variability (HRV) to train smarter. They dive into why elite athletes recover so quickly, the long-term value of zone 2 training, and how HRV reflects your resilience—not just your readiness. Joel shares lessons from two decades of working with fighters, Olympians, and NFL players, along with powerful insights from his own cardiovascular health journey. Whether you’re a high performer or simply want to live l...

In this episode, I’m joined by Dr. Ty Beal—global nutrition researcher and Senior Technical Specialist at the Global Alliance for Improved Nutrition (GAIN)—to uncover the hidden epidemic of micronutrient deficiencies worldwide. From food access and affordability to ultra-processed diets and nutrient bioavailability, we explore how modern food systems are failing billions and what needs to change to truly make the world healthier.

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In today's episode, I had the chance to speak to muscle physiology researcher and science communicator Dr. Lauren Colenso-Semple. Together, we unpack the common claims around hormones and training—from whether you should change your workouts based on your cycle, to the real effects of fasted cardio and birth control on performance and muscle growth. We also explore how menopause affects body composition, what the science actually supports when it comes to training differences between men and women, and why some of the most persistent myths about women’s physiology are based more on assumption than evidence.

What...

In this episode, I’m joined by Dr. Abbie Smith-Ryan—one of the leading researchers in exercise physiology and women’s metabolism—to unpack the science of how women should be training through perimenopause, postmenopause, and beyond. We dive into the physiological changes that impact body composition, performance, and recovery—and how to adjust training and nutrition to match.

We discuss:

This week in the studio, I'm joined by Dr. Nick Barringer—Army Ranger, performance nutrition expert, and one of the sharpest minds in military and metabolic health. Together, we cut through the noise around today's most controversial nutrition topics. If you’ve ever felt whiplash trying to make sense of conflicting headlines, this episode is your science-based compass.

What’s really going on with artificial sweeteners like sucralose and aspartame? Are seed oils toxic—or just misunderstood? And what’s the actual science behind popular supplements like creatine, testosterone boosters and fat burners?

Dr. Barringer brings two...

In this episode, I’m joined by Shaun Noorian—engineer, entrepreneur, and CEO of Empower Pharmacy, the largest compounding pharmacy in the world. With compounded GLP-1s making headlines and lawsuits from Big Pharma intensifying, Shaun joins me to pull back the curtain on the regulatory, financial, and ethical storm brewing behind the scenes.

Are compounded GLP-1s legal? Safe? Who controls drug pricing in the U.S., and why are Americans paying 10x more than Europeans for the same medication? And most importantly—what does all this mean for access, affordability, and patient care?

This e...

In this episode, I’m joined by Dr. Melanie Cree—physician-scientist, pediatric endocrinologist, and one of the leading researchers redefining how we understand and treat Polycystic Ovary Syndrome (PCOS). PCOS affects millions of women, yet it's still underdiagnosed, misunderstood, and often mistreated. Dr. Cree cuts through the confusion, offering a deeply scientific yet compassionate look at what’s really driving this complex condition—from insulin resistance and mitochondrial dysfunction to skeletal muscle quality and fertility trajectories across a woman’s lifespan.

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In this episode, I’m joined by Dr. Jocelyn Wittstein—orthopedic surgeon, sports medicine expert, and Associate Professor at Duke University—for a powerful and practical conversation about  bone and joint health across the lifespan. From the challenges of frozen shoulder and arthritis to the truth about running and menopause hormone therapy, this episode is your definitive guide to staying strong, mobile, and pain-free well into your 40s, 50s, and beyond.

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In this episode, I’m joined by Dr. Shane Kronstedt—former Navy SEAL, physician, surgical resident, and most importantly, my husband—for a powerful conversation about discipline, resilience, and the real-life moments that define us. From his early years of martial arts and mixed martial arts to surviving Hell Week and life-or-death missions in Afghanistan and Uganda, Shane shares how pressure creates clarity, why mindset matters most, and what it truly means to lead by example. This deeply personal episode gives you a rare glimpse into the man behind the mission.

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Jeff Krasno’s personal health transformation—reversing diabetes, shedding 60 pounds, and reclaiming his health at age 50—is a masterclass in what he calls “good stress.” In this episode, we dive into the simple but powerful idea that discomfort might just be the medicine we all need. Jeff, the founder of Commune and host of the Commune podcast, shares how fasting, cold exposure, resistance training, and attention to modern habits helped him regain his energy, build muscle, and thrive.

Together, we discuss how metabolic dysfunction has become the norm, how adaptive stress responses can be harnessed to reverse chronic il...

Nelson Vergel’s story is one of resilience, perseverance, and an unrelenting drive to defy the odds. In the mid-1980s, he was handed what many would have considered a death sentence—an HIV diagnosis at a time when there were no effective treatments, no clear answers, and little hope. Today, he is a beacon of knowledge and empowerment for those seeking to take control of their health, whether they are dealing with wasting conditions, hormone deficiencies, or simply aiming for peak performance. Nelson has spent decades researching and advocating for hormone health, muscle preservation, and medical autonomy, particularly for...

Dr. James Hill—a expert on obesity, metabolism, and long-term weight management—joins me this week to unpack the biggest challenges in sustainable fat loss. Dr. Hill has spent decades researching weight control and the factors that determine whether people can keep weight off long-term. We discuss the science behind energy balance, metabolic flexibility, and why long-term weight loss is about more than just diet and exercise. He shares insights from his groundbreaking work with the National Weight Control Registry, the role of GLP-1 medications, and why physical activity is the key to preventing weight regain.

We cove...

In this episode, Dr. Abraham Morgentaler—an expert in urology and hormone health—helps unpack the biggest myths and misconceptions surrounding testosterone therapy for both men and women. He shares his pioneering research on testosterone replacement therapy, challenging outdated fears about its link to prostate cancer and highlighting the latest findings on how hormone therapy can impact overall health, libido, and longevity. The conversation explores the controversial history of testosterone in medicine, the common mismanagement of hormone deficiencies, and why free testosterone may be one of the most important markers for health.

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Misinformation in nutrition is rampant. From demonizing red meat to hyping plant-based diets, conflicting advice has left many people confused about what’s truly evidence-based. In this episode, I am joined by Dr. Bradley Johnston, an expert in evidence-based nutrition and public health policies, to separate fact from fiction. With nearly 200 peer-reviewed publications, Dr. Johnston has challenged conventional wisdom—including recommendations from major organizations like the World Health Organization. He shares how evidence-based practices should guide our dietary choices, the importance of systematic reviews and meta-analyses, and how cognitive biases influence the research we trust.

Key Points:

In this episode, I sit down with Dr. Kristy Hamilton, a board-certified plastic surgeon, to explore the latest advancements in aesthetic medicine, the impact of social media on beauty standards, and the reality of breast implant illness. Dr. Hamilton shares her expert insights on facial rejuvenation, fat transfer, the safety of fillers, and new biostimulators while debunking common myths around plastic surgery. We also dive deep into the controversial rise of explant surgeries, the latest data on BII, and how surgical and non-surgical options can help individuals feel more confident in their skin. From the influence of celebrity procedures...

Today, I welcome Dr. Donald Layman back to The Dr. Gabrielle Lyon Show for a deep dive into his decades of protein research, the flaws in dietary guidelines, and the evolving landscape of nutrition. Together, we explore the real reasons behind the obesity epidemic, why decades of dietary advice have led us astray, and how we can reclaim metabolic health through high-quality protein intake. Dr. Layman shares compelling research on protein requirements, nutrient density, and how misleading narratives around fat and cholesterol have shaped our food choices. This conversation will challenge what you think you know about nutrition and...

Today, I welcome ultra-endurance athlete and world record holder Zach Bitter to The Dr. Gabrielle Lyon Show for an insightful conversation on the extreme physical and mental demands of ultra-marathons. Zach shares his mindset strategies for overcoming the inevitable dark moments in long-distance races, including visualization techniques and the importance of mental resilience in performance.

We also dive into personalized nutrition and training adaptations, as Zach details his transition from a high-carb to a low-carb diet and how it has influenced his endurance, recovery, and overall performance. Our discussion highlights the importance of metabolic flexibility, optimizing fuel...

Today, I welcome Dr. Heather Leidy to The Dr. Gabrielle Lyon Show for an in-depth conversation about the evolving landscape of nutrition science. Together, they tackle pressing topics like the future of the U.S. Dietary Guidelines, the impact of protein timing, and the importance of protein quality in supporting health and mitigating frailty. Dr. Leidy highlights recent research that explores behavioral strategies for sustainable weight management, the role of animal-sourced foods in nutrient adequacy, and the effects of GLP-1 medications on diet and health outcomes.

Key Discussion Points:

Dr. Stephan Van Vliet joins us for an enlightening exploration of nutrition, agriculture, and human health. Our discussion navigates the often-overlooked complexities of food production, examining the nutritional differences between pasture-finished and grain-finished beef. We also uncover how maternal nutrition might set the stage for children's future dietary preferences. Dr. Van Vliet introduces the intriguing concept of the food matrix, emphasizing the profound impact of bioactive compounds in whole foods that go far beyond mere macronutrient content.

As we venture into the emerging field of food metabolomics, Dr. Van Vliet reveals how metabolites in plants and animals...

In this episode of The Dr. Gabrielle Lyon Show, I sit down with my friend, Dr. Allison Brager, a neurobiologist, researcher, and active-duty U.S. Army neuroscientist whose work redefines what we know about sleep and human performance. Allison’s expertise goes beyond the usual advice about getting eight hours of sleep. Instead, we explore how to optimize performance and resilience when life doesn’t allow for a perfect sleep routine—something we can all relate to.

Allison shares fascinating insights from her work with military special operations, studying how sleep deprivation impacts cognitive and physical performance in hig...

In this episode of The Dr. Gabrielle Lyon Show, Dr. Gabrielle Lyon sits down with Dr. Susanna Søberg, a leading expert in cold exposure and metabolism. They dive deep into the science behind cold plunging, the benefits of brown adipose tissue (BAT), and how minimal doses of cold can dramatically improve metabolic health, mental resilience, and overall well-being.

Dr. Søberg shares her personal journey from working as a nurse to becoming a PhD researcher in metabolism, uncovering the surprising role that brown fat plays in regulating blood sugar, burning fat, and improving cardiovascular health. The co...

In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Faidon Magkos, a leading expert in obesity and metabolism at the University of Copenhagen, to tackle one of the most debated topics in nutrition science – the root causes of obesity. We dive into the contrasting theories of energy balance and the carbohydrate-insulin model, shedding light on what the latest research reveals – and what remains unknown. Dr. Magkos also discusses how environmental factors, genetics, and muscle health shape metabolic outcomes.

Together, we discuss:

Dr. Kevin Maki, renowned scientist and co-founder of multiple biomedical research centers, joins us to demystify the world of nutrition science. With a career spanning decades in epidemiology and clinical trials, Dr. Maki dives into the evidence behind red meat, cholesterol, saturated fats, and the impact of dietary habits on heart health. Discover the truth behind common misconceptions and gain clarity on making informed dietary choices.

In This Episode:

• What does the science really say about red meat and cholesterol?

• Understanding the role of saturated fats in heart health

• How observational studie...

In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Mike Israetel, an exercise physiologist and co-founder of Renaissance Periodization, to break down the science of sustainable fat loss and muscle gain. We explore the essential strategies for transforming your physique without falling for quick fixes or fad diets. From macronutrient distribution to the critical role of resistance training, Dr. Israetel offers practical, science-backed guidance for anyone looking to optimize their health and fitness. From macronutrients to supplements, we cover it all! 

We dive into: 

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon is joined by Dr. Russell Surasky, a board-certified neurologist and addiction specialist, to discuss one of the most pressing issues of our time: addiction. With a deeply personal connection to the topic, Dr. Surasky sheds light on the reality of addiction as a chronic brain disease and dispels the myths that have fueled stigma for decades.

Dr. Surasky explains how addiction fundamentally alters brain function, the role of genetic susceptibility, and why opioids—particularly fentanyl—pose an unprecedented threat. He shares actionable insights into treatment options, inclu...

Join Dr. Gabrielle Lyon and Dr Christie Ballantyne, one of the world’s leading cardiologists, for an insightful conversation on the science behind cardiovascular health, metabolic wellness, and disease prevention. In this episode, Dr. Ballantyne shares groundbreaking research, the role of genetics, and practical steps you can take to optimize heart health. Whether it’s through diet, exercise, or understanding your unique health profile, this discussion is packed with actionable strategies to help you live a longer, healthier life.

💡 Key Topics Covered:

Dive into an extraordinary conversation with Dr. Gabrielle Lyon and Dr. Jamie Baum, Associate Professor and Director of the Center for Human Nutrition at the University of Arkansas. In this episode, we explore revolutionary topics:

The role of skeletal muscle in appetite regulation.

Cutting-edge research on perimenopause and postmenopause nutrition.

How dietary protein impacts health and weight management.

Surprising findings on protein supplementation and sleep quality.

The science behind muscle-brain crosstalk and its effects on aging.

Dr. Baum shares her journey into research focused on women's health...

The Dietary Guidelines Are Failing Us

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon is joined by Dr. Donald Layman, a world-renowned expert in protein metabolism and a pioneer in the field of nutritional science. With over 20 years of mentorship between them, Dr. Layman and Dr. Lyon dive deep into the flaws, myths, and future of U.S. Dietary Guidelines, offering a clear path to better health through smarter dietary decisions.

Dr. Layman shares his revolutionary perspective on why protein intake should focus on essential amino acids, how carbohydrates—not fats—are driv...

Testosterone Matters for Everyone

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to explore the science, benefits, and future of testosterone therapy. Shalin has been a driving force behind bringing Kyzatrex, an FDA-approved oral testosterone, to market—making testosterone therapy more accessible and effective for both men and women. From breaking down misconceptions to advocating for better access to hormone therapy, this conversation sheds light on how testosterone plays a crucial role in overall health and wellness.

Shalin shares his journey, discussing how hi...

Designing Confidence

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Heidi Somers, the founder of Buffbunny Collection, a dynamic and empowering fitness and lifestyle brand that has taken the industry by storm. From growing up in a small town in Alaska to becoming a successful entrepreneur, Heidi’s journey is a testament to the power of resilience, self-belief, and authenticity.

Heidi opens up about her humble beginnings, including her early struggles with weight and body image, and shares how these experiences fueled her passion to help other women feel st...

Raising Healthy Athletes

In this enlightening episode of the Dr. Gabrielle Lyon Show, we dive deep into the world of youth training and the crucial role it plays in long-term health and athletic development. Joined by Judd Leinhard, former Army Ranger, collegiate lineman, and expert in speed training, we explore how training children differs from adults, debunk common myths, and reveal the surprising truth about building strength and resilience in kids.

We dive into:

In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Layne Norton, a scientist and nutrition expert, to unpack the complex truths behind obesity, weight management, and diet myths. Together, we discuss what truly drives weight gain beyond the “calories in vs. calories out” model, exploring the impacts of hormones, metabolic rates, and lifestyle choices.

We dive into:

- How the body processes carbs, fats, and proteins

- Challenging the carb-insulin model of obesity

- Practical tips on meal structuring and muscle maintenance

- The sign...

Defying Aging

In this episode of the Dr. Gabrielle Lyon Show, I sit down with Dr. Vonda Wright, a pioneering orthopedic surgeon and women’s health advocate, to explore the powerful intersection of mobility, aging, and resilience. Dr. Wright shares her inspiring journey from growing up on a Kansas farm to becoming a leader in orthopedics, and how her non-traditional path shaped her approach to health and wellness.

We explore:

Whether you're curious about aging well, staying strong, or redefining your heal...

Resetting the Nervous System

In this episode of the Dr. Gabrielle Lyon Show, we dive deep into groundbreaking approaches for treating PTSD, anxiety, and depression with Dr. John How, an emergency physician turned mental health advocate. Dr. How introduces us to the Stellate Ganglion Block, a powerful and non-invasive procedure that's transforming how we manage trauma and mental health without relying solely on medications.

We explore:

Breaking the Cycle

In this episode of the Dr. Gabrielle Lyon Show, I sit down with the incredible Thais Gibson, an expert in attachment theory and personal development. Together, we dive deep into the fascinating world of attachment styles and explore how early childhood experiences shape our emotional patterns, relationships, and even our overall health.

We cover:

Can you Build Muscle without Heavy Lifting?

Join Dr. Gabrielle Lyon as she sits down with Dr. Jeremy Loenneke, an associate professor of exercise science at the University of Mississippi and one of the world’s leading experts in blood flow restriction (BFR) training. They discuss the science behind skeletal muscle adaptation, how BFR can help you get stronger without heavy weights, and why muscle growth and strength aren’t always the same thing.

Dr. Loenneke shares insights on how BFR works—using low loads to trigger muscle adaptation and growth—and the potential benefits for reco...

Innovating Women’s Health

In this episode of The Dr. Gabrielle Lyon Show, I sit down with the incredible Cindy Eckert—serial entrepreneur, founder of Sprout Pharmaceuticals, and the driving force behind Addyi (commonly known as “the female Viagra”). Cindy shares her groundbreaking journey in advocating for women’s sexual health, challenging the medical system, and fighting for equal treatment in medicine.

Cindy reveals the startling double standards between male and female sexual health, recounting her experiences bringing Addyi to market and navigating the resistance she faced. Together, we dive deep into why women’s pleasure, he...

Building Muscle, Preventing Injury

In this episode we sit down with Dr. Jordan Shallow, chiropractor, strength and conditioning coach, and founder of Prescript. Dr. Shallow works with top athletes from the NFL, NHL, UFC, and more, helping them stay injury-free and perform at their best.

We dive deep into the world of biomechanics and movement, discussing the critical importance of "physical empathy" — understanding how the body interacts with gravity — and why it’s key to both performance and injury prevention. Whether you're an elite athlete or just starting your fitness journey, Dr. Shallow’s principles can help...

In this episode of the Dr. Gabrielle Lyon Show, we welcome back neurophysiologist and human performance expert, Louisa Nicola. Together, we explore the powerful connection between exercise, cognitive function, and the prevention of Alzheimer's disease. With cutting-edge insights from Louisa’s recent research, we dive deep into the impact of resistance training, cardiovascular exercise, and lifestyle interventions on brain health and longevity.

In this episode, you’ll learn:

In this episode of the Dr. Gabrielle Lyon Show, we dive deep into the world of compounding pharmacies and the transformative power of anabolic steroids with special guest Shaun Noorian, founder of Empower Pharmacy, one of the largest compounding pharmacies in the U.S.

Join us as Shaun shares his personal journey from engineering to pharmacy, sparked by a life-changing back injury that led him to discover the benefits of testosterone therapy. We explore the critical role compounding pharmacies play in providing customized medications that can dramatically improve health outcomes, particularly for those dealing with hormonal imbalances...

Breaking Health Myths

In this episode of the Dr. Gabrielle Lyon Show, we sit down with Mari Llewellyn. Mari opens up about her incredible transformation journey, losing over 100 pounds and reclaiming her mental and physical health. From hitting rock bottom to building a thriving wellness empire, Mari shares invaluable insights into the importance of weight training, discipline, and self-reflection.

Tune in as Mari discusses the challenges of navigating health trends, the responsibilities that come with being a public figure, and the evolving landscape of women’s health. Whether you’re struggling with weight loss, mental heal...

Discover the groundbreaking science behind healthy aging in this episode of the Dr. Gabrielle Lyon Show!

Join Dr. Lyon as she sits down with Dr. Anurag Singh, an MD PhD with extensive research in immunology, to explore the incredible benefits of Urolithin A, a compound that's showing promise in protecting muscle health and enhancing mitochondrial function.

Dr. Singh shares his remarkable journey from medical school in India to becoming a leading researcher in the United States, where he’s been at the forefront of studying the impact of Urolithin A on aging. They dive deep in...

From Crisis to Confidence

In this episode of the Dr. Gabrielle Lyon Show, Dr. Lyon engages in an insightful conversation with Greg Scheinman, a successful entrepreneur, coach, and the creator of the Midlife Male movement. Greg's journey is a testament to the fact that midlife doesn't have to be a crisis—it can be a time of transformation, growth, and renewed purpose.

Greg opens up about his personal struggles with burnout, unhealthy habits, and the societal pressures that many men face as they navigate their 40s and 50s. He discusses the pivotal moment that led hi...

Emotional vs. Physical Hunger

Join Dr. Gabrielle Lyon as she sits down with Dr. Allan Bacon, who transitioned from a career in dental surgery to becoming a top nutrition and training coach. Dr. Allan shares his journey, offers powerful insights on sustainable weight loss, and breaks down the crucial differences between emotional and physical hunger. Discover practical strategies to overcome weight loss plateaus, optimize your meal frequency, and debunk common fitness myths. If you're ready to take control of your health, learn from the best, and get inspired to achieve your fitness goals.

Dr. Allan...

How to Maximize Muscle Growth

In this episode we welcome back Dr. Pat Davidson, a PhD in exercise physiology and former professor. Dr. Davidson, known for his impressive physique and deep knowledge, sheds light on the confusion surrounding effective training methods. Whether you're unsure about how much to lift or what kind of training to do, Dr. Davidson has you covered.

We cover Dr. Davidsons’ personal experiences, professional insights, and practical advice on how to think about and approach training. From discussing the best exercises for muscle growth to the role of aerobic fitness in lo...

Quality Food can change your Life!

In this special episode Dr. Lyon sits down with lead nutritionist Julia Mitchell for a discussion on achieving the body composition of your dreams! Julia shares her journey from bison ranching in Canada to becoming an integral part of Dr. Lyon's clinical practice, offering practical tips and insights to help you reach your health and fitness goals.

Julia Mitchell is a functional nutritionist who considers the context of a person’s physiological make-up, how they live, and what they want to achieve. One size does not fit all. Through th...

In this episode Dr. Lyon sits down with Dr. Erik Won, President and Chief Medical Officer of WAVE Neuroscience Biotechnology. Dr. Won shares his journey from being a Navy flight surgeon to leading groundbreaking research in brain health.

If you struggle with brain fog, depression, PTSD, or traumatic brain injury, this episode is for you. Learn about innovative treatments that are changing lives and providing hope for those suffering from brain-related conditions. Don’t miss this enlightening conversation on the future of neuroscience!

Dr. Erik Won is President and Chief Medical Officer of Wave Neuroscience, In...

I sit down with Dr. Mike Israetel, founder of RP Strength, to discuss the crucial role of skeletal muscle in health and longevity. We delve into the science behind muscle hypertrophy, strength maintenance, and why building muscle is essential as we age. Dr. Israetel shares evidence-based tips on effective strength training, the benefits of muscle mass for metabolic health, and how to overcome common misconceptions about strength training, especially for women. Tune in to learn how to maximize your muscle growth and improve your overall health, no matter your age!

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Renowned fitness expert Don Saladino shares his invaluable insights on health, wellness, and fitness. In this episode, we talk about the importance of discipline over motivation, the non-negotiable role of strength training in body composition, and practical tips for beginners looking to embark on their fitness journey. With a career spanning over a decade and a client list that includes Hollywood stars and top athletes, Don's approach combines simplicity with effectiveness.

Whether you're a fitness newbie or looking to refine your regimen, Don Saladino's expert advice will help you achieve your health and wellness goals.

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Dr. Andy Galpin, a leading muscle physiology expert, shares his unique insights on skeletal muscle biomarkers, the impact of sleep on health, and his philosophies on scientific information. With a career dedicated to enhancing the performance of top athletes and fighters, Dr. Galpin brings a fresh perspective on health and wellness that challenges conventional wisdom. Don't miss this deep dive into the mechanics of our muscles and learn how you can apply these insights to improve your own health and performance.

Exciting News! Dr. Andy Galpin has launched a brand new podcast! Dive deep...

Ever wondered how red and infrared light enhance your health and vitality? Join Dr. Alexis Cowan as she dives deep into the fascinating world of photobiomodulation, mitochondrial health, and the profound impact of natural light on our biology. From debunking myths about UV exposure to exploring the synergy between cold exposure and sunlight, this enlightening conversation offers practical insights for optimizing your daily environment to support overall well-being. Discover the secrets of harnessing sunlight and cold therapy to boost energy, improve sleep, and promote resilience. 

Whether you're curious about biohacking through light and nature or seeking evidence-based i...

Join Dr. Gabrielle Lyon and guest Dr. Madeleine Novich in an enlightening conversation that explores the essence of personal, relational, and collective identities. From dissecting the intricate dynamics of health prioritization to unveiling the power of healthy boundaries in relationships, each episode offers profound insights into achieving an elite identity. 

Dive into discussions on childhood nutrition, parenting strategies, and the transformative influence of collective thinking, as Dr. Lyon and Dr. Novich unravel the secrets to cultivating a life of purpose, resilience, and vitality. Tune in for practical tips and compelling stories that inspire listeners to elevate their l...

Ever wondered why your libido might be low or why things aren’t working quite the way they should? Join us as we uncover the surprising world of how medications and substances can shake up your sex life! Discover the real truth behind common medications like oral contraceptives and SSRIs and their impact on your sexual health.

In this episode, with Dr. Rena Malik we’ll also tackle crucial and taboo topics like genital health, the different types of orgasms women experience, and common insecurities about body image, scent, and sexual performance. Get tips on how to enha...

Join us as we uncover the extraordinary journey of Justin Gatlin, the fastest man alive and three times Olympic champion. In this episode, Justin shares how he transitioned from a young athlete with potential to a globally recognized sprinter.

Learn about his rigorous training regimen, the mental resilience that kept him at the top, and the challenges he overcame along the way.

Justin shares personal stories of overcoming challenges, including lifestyle adjustments and the mental strategies that kept him ahead of the competition. Discover what it takes to be a top athlete and how to...

Let’s take a look into the fascinating world of tendon health with Dr. Gerard D’Onofrio in this latest episode of the Dr. Gabrielle Lyon Show. Join us as we explore the crucial role of tendons in overall mobility and discuss the various factors impacting tendon functionality. Learn about the basics of how tendons work in harmony with muscles to support movement and what makes them vulnerable to injuries. Discover the significant influence of nutrients such as hydrolyzed collagen, leucine, and omega-3 fatty acids on tendon health, alongside the effects of hormonal changes and medications like fluoroquinolones and cort...

Dive deep into the fascinating world of gut health with Dr. Ken Brown, a physician and expert in the field. 

This episode explores how gut health impacts everything from nutrient absorption to overall well-being and even mental health.

Dr. Brown shares strategies to cultivate a diverse and healthy gut microbiome, the causes and treatment approaches for chronic constipation, including safe and effective laxative use, and the connection between gut health and muscle health.

Ready to take charge of your gut health? Tune in and gain valuable insights from Dr. Ken Brown.

👉 Get...

Dr. Jess Gwin, a recognized expert in nutritional sciences, unveils the profound role of proteins and essential amino acids in our diet. We discuss the critical importance of protein quality and its impact on more than just muscle health—exploring how it influences hunger, brain function, and satiety.

Delving into the nuances of daily protein optimization, Dr. Gwin explains why all proteins aren't created equal and the implications for dietary guidelines. The conversation also covers the limitations of current dietary guidelines and what future research is needed to improve public health recommendations.

Dr. Gwin provides in...

Renowned expert Dr. Mo Khera sheds light on common sexual dysfunctions in both men and women, emphasizing the startling connection between erectile dysfunction and heart attacks.

We delve into testosterone, exploring why low levels might not always warrant treatment and the importance of considering symptoms alongside testosterone levels for therapy decisions.

The conversation extends to female sexual dysfunction, stressing the significance of addressing common symptoms and a woman's unique concerns.

Dr. Khera speaks to the role of testosterone replacement therapy (TRT), providing in-depth insights and dispelling myths about increased risks of prostate cancer...

Casey Means, MD is a Stanford-trained physician, Chief Medical Officer and Co-founder of metabolic health company Levels, and Associate Editor of the International Journal of Disease Reversal and Prevention.

Americans are getting sicker year after year, despite ever-increasing healthcare spending. Dr. Means believes we are focusing on the wrong problem entirely.

Metabolic dysfunction.

In this podcast, expect to learn about the world of cellular health, the five pillars that contribute to optimal function, the best ways to nourish your cells with the right nutrients and foods, the unique needs of women's health, including...

As a lifelong educator Matt Beaudreau has a reputation as a provocative thought leader in educational and personal development practices. He is a two-time featured TEDx speaker and he was named Corporate Trainer of the Year at Stanford University, having spoken to over 250,000 people .

In this episode we discuss:

This episode is brought to you by PaleoValley, Ned, MUD/WTR, InsideTracker, 1st...

Jessie Inchauspé is a French biochemist and New York Times bestselling author. She is on a mission to translate cutting-edge science into easy tips to help people improve their physical and mental health. In her books Glucose Revolution and The Glucose Goddess Method, which sold over 1 million copies worldwide in 40 languages, she shares her startling discovery about the essential role of blood sugar in every aspect of our lives, and the surprising hacks to optimize it. Jessie is the founder of the popular Instagram account @GlucoseGoddess, where she teaches over 3 million people about transformative food habits. She holds a B...

Darren G. Candow, Ph.D., CSEP-CEP, is Professor and Director of the Aging Muscle and Bone Health Laboratory in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. Dr. Candow has published over 125 peer-refereed journal manuscripts (h-index: 43, i10-index: 89), supervised over 20 MSc and PhD students and received research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, National Institutes of Health, and the Nutricia Research Foundation. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition, Nutrients...

B. Christopher Frueh, PhD is a professor of psychology at the University of Hawaii. He has over thirty years of professional experience working with military veterans, servicemembers, special operators, private defense contractors, and firefighters; and has conducted clinical trials, epidemiology, historical, and neuroscience research. He has co-authored over 300 scientific publications. He was previously a professor of psychiatry at Medical University of South Carolina and Baylor College of Medicine. He has published commentaries in the National Review, Huffington Post, New York Times, Time, Men’s Journal, and Special Operation Association of America.

In this episode we discuss

Dr. Donald Layman is Professor Emeritus in the Department of Food Science & Human Nutrition at the University of Illinois at Urbana-Champaign. Dr. Layman served on the faculty at the University of Illinois from 1977 – 2012. Dr. Layman has been a leader in research about protein, nutrition for athletic performance, obesity, diabetes and cardiovascular health. Dr. Layman has over 100 peer-reviewed publications. He has received numerous awards for his research from the American Society for Nutrition and the National Institutes for Health and for his nutrition teaching. Dr. Layman served as Associate Editor of The Journal of Nutrition and the Journal of Nutrition Ed...

Dr. Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur.

In this episode we discuss:

This episode is brought to you by Vivo Health, Thesis, LMNT, InsideTracker, 1stPhorm

Known as America's Holistic Plastic Surgeon®, Anthony Youn, M.D. F.A.C.S is a nationally-recognized, board-certified plastic surgeon. Recognized as a leader in his field, he is the author of the best-selling books “The Age Fix," "In Stitches," and “Playing God.” His public television special, The Age Fix with Dr. Anthony Youn, has been viewed by millions.  Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show. He is the most followed plastic surgeon on social media, with over 4.5 million subscribers on his YouTube Channel and 8 million followers on TikTok. His new book, “Younger for Life” is a...

Gary Taubes is an investigative science and health journalist, the author of Rethinking Diabetes, The Case for Keto, The Case Against Sugar, Why We Get Fat and Good Calories, Bad Calories (published as The Diet Delusion in the UK). Taubes is a former staff writer for Discover and correspondent for the journal Science. His writing has also appeared in The New York Times Magazine, The Atlantic, and Esquire, and has been included in numerous Best of anthologies, including The Best of the Best American Science Writing (2010). He has received three Science in Society Journalism Awards from the U.S. National Ass...

Dr. Sportelli is a Medical Physician who received a Bachelors degree in Biology as well as a Masters of Science degree in Biology from Montclair State University. He attended NYIT School of Osteopathic Medicine, and upon graduating with Honors in clinical science, Dr. Sportelli pursued a Graduate Medical Internship year in General Family Medicine at NJ Medical School. He is the Associate Program Director of NY Medical College Psychiatry Residency at Prime Health, Adjunct Clinical Assistant Professor of Touro School Medicine and a member of the Advisory Board of NYIT School of Osteopathic Medicine. Dr. Sportelli is Board Certified...

Dr Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading major medical center in Seattle. His research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He has an undergraduate degree in mechanical engineering and utilizes engineering principles when dealing with complex systems such as human health and nutrition.

In this episode we discuss:

This special live episode from the first annual Forever Strong Summit features influential speakers from various fields, including nutrition, business, and personal development. Hear from Michelle Shapiro–functional nutritionist, Ben Newman–performance coach, speaker, and author, Matt Schneider–entrepreneur, Jen Gottlieb–entrepreneur, speaker, and author, Don Saladino–celebrity coach and fitness entrepreneur. If you want to learn from top influencers and elevate your game this lively discussion is for you!

In this episode we discuss:

Thomas DeLauer is a Nutritionist and Expert in Diet, Cognitive Nutrition and Performance. He is motivated by a guiding ethos of integrated optimization: if you perform better, so does the world. Thomas reaches more than 15 million viewers monthly (on average) through his Youtube channel, where he translates experience and learning from his own health transformation as well as experience working with Special Operations as well as Professional Athletes to his dedicated community of 3.5 million subscribers.

In this episode we discuss:

Nicolas Verhoeven is a PhD Candidate in Molecular Medicine who works in a mitochondria and autophagy laboratory; he also holds a Masters in Exercise Physiology. Verhoeven runs Physionic, a brand that bridges the gap between scientific studies and the public’s understanding by opening studies, showing and explaining the data, and explaining the physiology that underlies that data. One of his missions is to improve the public’s understanding of the scientific literature without sacrificing the details (or the fun!).

In this episode we discuss:

Cholsoon Jang, PhD is an Assistant Professor of Biological Chemistry at the University of California Irvine School of Medicine. Dr. Jang obtained bachelor’s and master’s degrees from Korea Advanced Institute of Science and Technology. He then received PhD from Harvard University and completed postdoctoral training at Princeton University. Dr. Jang’s laboratory focuses on understanding how dietary nutrients are processed in the body and exert health-beneficial or detrimental effects. Dr. Jang received prestigious awards such as Pinnacle Research Award from the American Association for the Study of Liver Disease and Edward Mallinckrodt Jr. Foundation Award, and several resear...

Kevin A. Murach, Ph.D., completed a master’s degree in Exercise Physiology at James Madison University in Harrisonburg, Virginia, then earned his Ph.D. in Human Bioenergetics from the Ball State Human Performance Laboratory in Muncie, Indiana. After Ball State, Dr. Murach spent six years as a post-doctoral fellow/scholar studying muscle stem cells at the University of Kentucky Center for Muscle Biology in Lexington under the guidance of Drs. Charlotte Peterson and John McCarthy. He now is an Assistant Professor at the University of Arkansas. His current research uses human muscle samples, primary cell culture and genetically modif...

Dr. Mary Claire Haver is board certified in Obstetrics and Gynecology and is a Certified Culinary Medicine Specialist from Tulane University. She is a Louisiana State University Medical Center graduate and completed her Obstetrics and Gynecology residency at the University of Texas Medical Branch (UTMB). She is also a Certified Menopause Specialist through The Menopause Society. Dr. Haver was a clinical professor at UTMB and The University of Texas Health Science Center at Houston. Dr. Haver has served as a Hospitalist, Associate Residency Director, and Assistant Professor in her career. In 2021 she opened Mary Claire Wellness, a clinic dedicated...

Mark Bell has spent most of his 20s and 30s working on becoming a world ranked powerlifter. He is currently ranked in the top 10 of all-time powerlifters, with a total of 2,628 lb. He has squatted 1,080 lbs, bench pressed 854 lbs, and deadlifted 766 lbs. He and his wife, Andee, own and operate Super Training Products Inc., a multi-million dollar fitness business that they started in 2010.

In this episode we discuss:

Dr. Christopher Fry is a tenured Associate Professor in the Department of Athletic Training and Clinical Nutrition at the University of Kentucky, and he serves as the Associate Director of the Center for Muscle Biology. Chris completed a BS in Biology at Baylor University, PhD in biomedical sciences at the University of Texas Medical Branch and postdoctoral training in muscle physiology at the University of Kentucky. His research is funded by several grants through the National Institutes of Health (NIH), and he has received several awards for his research. Over the course of his career, Dr. Fry has created...

Nathalia is a fitness professional with over 15 years of experience, and no stranger to challenges as a former bikini Olympia champion, which is the biggest bodybuilding competition in the world.  Her work and knowledge has allowed her to be featured in several national and international magazines covers and articles like: Muscle & Fitness Hers , Oxygen, Shape , Cosmopolitan, The Daily Mail, and Muscular Development to name a few. 

In this episode we discuss:

An American conservationist, writer, actor, producer, motivational speaker, and former Force Reconnaissance Marine. He is best known for portraying himself in the HBO miniseries Generation Kill. He can also be seen in Apocalypse Man, UK channel 4’s SAS: Who Dares Wins, and the Fox series Special Forces: World's Toughest Test. He has also contributed to the multiple BAFTA nominated documentary series once upon a time in Iraq and as the character ”Reyes" in the video game call of duty: modern warfare.

In this episode we discuss: