The  Wine Lab

The Wine Lab

By: Andreea Botezatu

Language: en-us

Categories: Science, Life

A sciency podcast series about wine, chemistry, flavor, smell and everything in between hosted by wine and sensory scientist, book worm and food aficionado, Andreea Botezatu.

Episodes

Madeira - From Ocean Voyages to Attic Barrels
Dec 15, 2025

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Madeira is one of the most resilient wines ever produced. Fortified during fermentation, intentionally heated, and slowly oxidized, it defies many of the rules that govern wine aging and thrives because of it.

In this episode of The Wine Lab, we explore how Madeira’s unique production methods developed through long ocean voyages, how fortification with highly rectified grape spirit shapes sweetness and stability, and why heating methods like estufagem and canteiro create such extraordinary longevity. Along the way, we trace Madeira’s chemical evolution, its role in h...

Duration: 00:11:17
Fortified by the Douro: The Story of Port Wine
Dec 08, 2025

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Step into the steep, sunlit terraces of Portugal’s Douro Valley and explore how landscape, law, chemistry, and culture shaped one of the world’s most distinctive wines. 

In this episode of The Wine Lab, host Dr. Andreea Botezatu traces the story of Port from the Douro’s historic demarcation in 1756 to the precise moment fermentation is stopped with grape spirit. 

Follow the evolution of styles, from ruby’s vibrant fruit to the layered depth of long-aged tawnies, and learn how traditional lagares, the Benefício vineyar...

Duration: 00:11:26
Under the Flor: The Science and Soul of Sherry
Dec 01, 2025

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In this episode of The Wine Lab, host Dr. Andreea Botezatu explores the scientific brilliance and cultural heritage of Sherry. From Andalucía’s luminous albariza soils to the flor yeasts that sculpt its aromatic identity, Sherry emerges as a wine shaped by geology, microbiology, and centuries of human expertise. We examine how fortification, performed after fermentation, determines whether a wine will age biologically as a Fino or oxidatively as an Oloroso, and how the solera system maintains continuity acro...

Duration: 00:11:52
Winter in a Glass: The Story and Science of Icewine
Nov 24, 2025

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Icewine is one of the most challenging and extraordinary wines ever produced,a liquid born from winter itself. In this episode of The Wine Lab, Dr. Andreea Botezatu explores how a frozen accident in 1794 became one of the modern wine world’s most coveted styles. We travel from Germany to Canada’s Niagara Peninsula, through vineyards picked at –10°C, and into fermenters battling extreme osmotic stress, soaring Brix, and yeast pushed to its limits.

From the brutal harvest nights to the chemistry of freezing, from osmotol...

Duration: 00:13:49
Pét-Nat: Ancient Method, Modern Mood
Nov 17, 2025

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Before Champagne perfected the art of bubbles, there was pétillant naturel or pét-nat -  the ancestral, gracefully imperfect  way to make sparkling wine. In this episode of The Wine Lab, we explore the chemistry, the history, and the somewhat controlled chaos that defines this naturally effervescent style.

Why does pét-nat fizz differently? What actually happens when fermentation finishes inside a sealed bottle? And why are winemakers, from the Loire to California, falling back in love with this centuries-old technique?

From carbo...

Duration: 00:11:51
Steel, Bubbles, and Fruit: Inside the Making of Prosecco
Nov 03, 2025

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What makes Prosecco so different from Champagne or Cava?


 In this episode, Andreea takes you inside the tanks (almost literally) to explore the Charmat method, the clever bit of winemaking engineering that gives Prosecco its bright, floral personality.

We’ll look at how Glera grapes, stainless-steel pressure tanks, and precise temperature control create a wine built on freshness rather than aging. You’ll learn what “tirage” and “dosage” mean in Prosecco, why it skips lees aging, and how its chemistry translates into texture, aroma, and food pair...

Duration: 00:10:14
Champagne & Cava: Two Ways to Catch a Bubble (or proof that joy can be engineered - one tiny bubble at a time)
Oct 27, 2025

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Across Europe, bubbles tell stories. In this episode of The Wine Lab, we explore two sparkling legends - Champagne and Cava -  both born from the same meticulous process yet shaped by different lands, grapes, and histories.

We’ll uncover how the traditional method transforms still wine into a storm of fine bubbles, why the same Brut label can taste drier in Champagne than in Cava, and how yeast, sugar, and time create that signature creamy texture and brioche aroma...

Duration: 00:09:29
Inside the Barrel: Where Wine Meets Oak, Fire, and Time
Oct 20, 2025

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In this episode of The Wine Lab, Andreea takes you inside one of winemaking’s most iconic tools — the oak barrel. From Celtic craftsmanship to modern coopering, we’ll explore how fire, oxygen, and time turn simple wood into a vessel of transformation.

Discover why oak became the gold standard, what happens during toasting, and how micro-oxygenation softens tannins and stabilizes color. Learn about the differences between French, American, and Hungarian oak, the chemistry behind aging, and even the future of sustainable cooperage — including experimental ideas like biochar...

Duration: 00:13:38
From Leather to Cabernet: The Story of Tannins
Oct 13, 2025

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In this episode of The Wine Lab, we explore the science and story of tannins: what they are, where they come from, and why some wines feel silky while others grip your gums.

From the ancient craft of leather tanning to modern barrel aging, we trace how these polyphenolic compounds shape wine’s structure, color, and longevity. We’ll look at how fermentation temperature, pH, and rising alcohol shift what gets extracted from skins and seeds — and how acidity changes the way tannins feel on your palate.

Y...

Duration: 00:11:44
Wine with Spirit: The World of Fortified Wines
Oct 06, 2025

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What do Port, Sherry, Madeira, Marsala, and Vermouth all have in common? They’re wines with an extra ingredient — spirit. In this episode of The Wine Lab, Dr. Andreea Botezatu explores how fortification began as a practical solution for preserving wine on long sea voyages and evolved into a craft that shaped trade, taste, and culture.

From Shakespeare’s Falstaff praising “sack” to George Washington’s love for Madeira, we’ll travel through history and a little chemistry to understand what makes fortified wines so endur...

Duration: 00:08:59
Dom Perignon - The Monk Who Didn’t Invent Champagne
Sep 29, 2025

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Everyone knows the story of Dom Pérignon — the monk who invented Champagne and declared he was “tasting the stars.” But history tells a very different tale. In this episode of The Wine Lab, we uncover the truth behind one of wine’s most enduring myths.

Dom Pérignon didn’t create sparkling wine at all! In fact, he spent much of his life trying to eliminate bubbles from the Abbey of Hautvillers’ wines. Yet his innovations in grape selection, blending, and cellar practices laid the foundation for the Champa...

Duration: 00:07:52
Roots of Disaster: The Phylloxera Story. A tiny insect nearly erased wine from history — discover how science, stubbornness, and a Texan saved it.
Sep 22, 2025

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In the late 1800s, an almost invisible insect began destroying Europe’s vineyards. This episode of The Wine Lab takes you inside the phylloxera crisis — from the first mysterious vine deaths in France to the desperate experiments, scientific breakthroughs, and global collaboration that saved wine from near extinction. Along the way, we meet the heroes of the story, including Texan horticulturist T.V. Munson, whose work with American rootstocks helped rescue French viticulture. Discover how this tiny pest reshaped winemaking traditions, why grafted vines are now the global standard, and...

Duration: 00:10:10
From Bark to Bottle: The Cork Chronicles
Sep 15, 2025

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Cork is everywhere in the world of wine, from the quiet of a cellar to the noise of a celebration. But how did this small stopper come to influence the way wines age, the rituals of opening a bottle, and even the way we think about quality? In this episode of The Wine Lab, we explore the science, the history, and the culture wrapped up in every cork, and ponder why it remains central to wine today. 

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Duration: 00:10:41
Sweet Lies and Dry Truths: Sugar in Wine
Sep 08, 2025

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 Is wine really “full of sugar”? What about those “zero sugar” labels, or the idea that wine is keto-friendly? In this episode of The Wine Lab, Andreea breaks down what you need to know about sugar in wine — from grapes on the vine to yeast in the tank, from chaptalization in Burgundy to back-sweetening in Riesling, and from Champagne dosage to carbs and calories. Along the way, we’ll uncover what’s legal, what’s marketing, and what really ends up in your glass. 

Glossary

Glucose & Fru...

Duration: 00:08:25
Wine in Art – From Ancient Gods to Pop Culture
Sep 01, 2025

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 Wine shimmers across the history of art: painted on Egyptian tomb walls, poured into Greek amphorae, celebrated in Roman mosaics, lifted in Renaissance chalices, and glowing in Impressionist picnics. In this episode of The Wine Lab, we follow its journey through image, poetry, and song, tracing how wine has carried sacred meanings, earthly joys, and artistic inspiration across millennia—ending with Pablo Neruda’s luminous Ode to Wine.


🍷 Glossary of Lesser-Known Terms

Amphora
A tall, two-handled clay vessel used in ancie...

Duration: 00:15:45
Headaches, Hipsters, and the Myth of Sulfite-Free Natural Wine
Aug 25, 2025

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 In this episode of The Wine Lab, host Andreea Botezatu unpacks the misunderstood world of sulfites in wine — what they are, what they do, and why that warning label exists. From antioxidant chemistry to ancient winemaking tricks, we look at how sulfur dioxide protects wine, explore common myths - like the one about sulfites and headaches - and even dive into the science of those rare sulfite sensitivities. Expect a splash of history, a little rock ‘n’ roll, and a few nerdy detours into redox chemistry. 

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Duration: 00:07:54
The Oldest Wines Ever Discovered – Stories from the Ancient World
Aug 18, 2025

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From Neolithic pottery shards to golden amphorae sealed for millennia, the world’s oldest wines tell us more than just what ancient people drank — they reveal how wine shaped trade, ritual, and daily life across civilizations. In this episode, we journey through some of the most remarkable archaeological wine finds, explore the science used to identify them, and imagine what these ancient vintages might have tasted like.


Glossary

Qvevri (also spelled Kvevri)

Large, egg-shaped clay vessels used in Geor...

Duration: 00:09:43
Under Pressure: The Craft and Chemistry of Sparkling Wine. How do the world’s finest bubbles get into your glass? We explore the science, regions, and traditions of sparkling wine.
Aug 11, 2025

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 From royal courts in 17th-century France to today’s celebrations around the world, sparkling wine has captured attention for centuries. In this episode of The Wine Lab, host Andreea Botezatu explains how sparkling wines are made, from traditional Champagne techniques to Prosecco’s Charmat method and beyond. We’ll look at the role of secondary fermentation, explore different sweetness levels, highlight the major regions producing sparkling wine, and share the story of La Veuve Clicquot, the woman who changed sparkling wine production forever. 

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Duration: 00:10:02
Native Rebels and Cultured Icons: Yeast in the Cellar - How yeast drives complexity, unpredictability, and style in winemaking.
Aug 04, 2025

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In this episode of The Wine Lab, we explore the unseen world of yeast—the microscopic winemakers transforming grape juice into wine. 

From lab-selected commercial strains to wild, spontaneous fermentations and even wineries culturing their own native yeasts, we uncover how these tiny organisms shape wine’s flavor, texture, and identity. 

Along the way, we touch on yeast’s long history in human culture—from bread to beer to Bordeaux. 

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Duration: 00:08:28
Smells Like Wine Spirit: The Science of Aroma
Jul 28, 2025

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Why does a glass of wine smell like blackberries, jasmine, or freshly cut herbs—when it’s made entirely from grapes? 

In this episode, we explore the complex and fascinating science of wine aroma.

 From compounds naturally found in grapes and flowers to the transformative role of fermentation and microbes, we trace how scent molecules form, evolve, and interact with our senses. 

We’ll also examine how genetics, memory, and culture shape the way we experience wine, and why no two noses interpret it quite...

Duration: 00:10:17
Malolactic: Magic or Mayhem?
Jul 21, 2025

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In this episode of The Wine Lab, we swirl through the science of malolactic fermentation (MLF), the process that can soften wine and elevate complexity, but also invite spoilage and instability, especially in high pH wines. We break down what MLF actually is, why winemakers use it, when they avoid it, and how to manage its benefits and risks with precision.

Perfect for winemakers, wine students, and curious wine lovers.

For more in-depth information on this topic you can watch this webinar, which is part...

Duration: 00:11:01
Sour Grapes, Sweet Solutions: How Verjus Could Help Winemakers Beat the Heat
Jul 14, 2025

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Can a splash of sour grape juice make wines better in a warming world? 

In this episode, we explore how verjus—juice from unripe grapes—can improve wine chemistry, reduce alcohol, and enhance sustainability in hot-climate winemaking. Based on research from Texas A&M University.


 👉 Read the full paper

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Duration: 00:05:19
Uncorking Haloanisoles in Wine
Jul 14, 2025

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We’ve all heard of “corked” wine — but what if that wet dog smell isn’t the cork’s fault at all? In this episode of The Wine Lab, we explore the fascinating and frustrating world of haloanisoles: TCA, TBA, TeCA, PCA, and their highly aromatic footprint in wine.

These powerful compounds can travel through the air, cling to barrels and insulation, and even sabotage stainless steel tanks. Learn about their origins, their impact on sensory perception, the limits of closures like screwcaps and synthetic corks, and t...

Duration: 00:06:01
Cluster Thinning and Wine Quality: Myth, Method, or Must?
Jul 14, 2025

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Can fewer grapes mean better wine? In this episode of The Wine Lab, Dr. Andreea Botezatu explores the science behind cluster thinning, a time-honored but hotly debated vineyard practice. Drawing from a recent narrative systematic review, we break down what the research really says about its impact on wine aroma, phenolics, sensory quality, and economic viability. Whether you’re managing a vineyard or just love wine science, this episode offers practical insights to help you make informed decisions.

📄 Read the full...

Duration: 00:06:35