Dental Formulator's Playbook

Is your mouthwash truly neutralizing odor-causing compounds—or just giving bad breath a minty disguise?

In this deep-dive episode of Dental Formulator’s Playbook, Dr. Robert L. Karlinsey and co-host Tami go full-on formula forensics, comparing the science behind two leading mouthwash brands: TheraBreath and SmartMouth. From the mechanisms of sodium chlorite and zinc chloride to preservative systems, patent strategy, and flavor chemistry, the duo unpack how formulation choices shape both performance and perception.

Whether you’re a clinician, formulator, or curious consumer tackling chronic halitosis, this episode delivers a data-driven look at what your mouthw...

Do you brush and floss every day yet still struggle with bad breath that just won’t go away?

In this revealing episode of Dental Formulator’s Playbook, Dr. Robert L. Karlinsey and co-host Tami explore the underexamined science of halitosis — debunking myths, exposing the biochemical causes of bad breath, and dissecting why certain mouthwashes work while others fall short.

From volatile sulfur compounds (VSCs) to regulatory blind spots, they explain why halitosis persists, which ingredients actually make a difference, and how sodium chlorite performs (or fails) depending on activation conditions and formulation design.

This...

Do you really know what’s in your mouthwash—or are marketing claims rinsing away the truth?

In this episode of Dental Formulator’s Playbook, Dr. Robert L. Karlinsey and co-host Tami conduct a “formula forensics” breakdown of three mouthwash types—alcohol-based essential-oil rinses (Listerine Antiseptic), zero-alcohol cosmetic rinses, and CPC-based clinical formulations. With scientific precision, they dissect ingredient labels, debunk marketing claims, and clarify what truly makes a mouthwash effective and safe.

The episode highlights the importance of formulation strategy, regulatory compliance, and proper testing—essential insights for brands, formulators, and curious consumers alike. 

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Duration: 01:24:25

Is mouthwash really destroying your oral microbiome—or can the right formulas actually help it thrive?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami tackle the widespread myth that all mouthwashes harm the oral microbiome. They review clinical evidence on cetylpyridinium chloride (CPC) and essential-oil rinses, showing how some formulas can selectively reduce problem bacteria while preserving—or even supporting—beneficial species. The discussion covers how the microbiome adapts to treatment, why claims must be evidence-based, and a fresh idea: rotating oral-care products seasonally to help maintain a balanced biofilm. Dr. Rob also undersco...

Could the bacteria in your mouth actually be protecting your heart and lowering your blood pressure?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami explore the complex ecosystem of the oral microbiome, focusing on nitrate-reducing bacteria and their role in both oral and systemic health. They examine the influence of diet, hygiene, and genetics on microbial balance and the implications of oral care products—like chlorhexidine and potassium nitrate—on beneficial bacteria. The conversation highlights why the oral microbiome is more than just “good vs. bad” bacteria, how nitrate reduction contributes to nitric oxide prod...

Do DIY teeth whitening hacks like banana peels, charcoal, or turmeric really work—or are they quietly damaging your enamel?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami take a critical look at popular at-home teeth whitening remedies—from banana peels and charcoal to baking soda, turmeric, and acidic fruits. They unpack the science behind these viral trends, separating fact from fiction. While many natural approaches lack scientific evidence or pose risks to enamel, enzyme-based alternatives and PAP (a peroxide substitute) show real potential. The conversation emphasizes that peroxide remains the gold standard for wh...

Are whiter teeth worth the risk—or is your smile safer without the hype of quick-fix whitening treatments?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami break down the science, risks, and realities behind popular dental whitening techniques. From enamel microabrasion to peroxide-based bleaching, they explore what really works, what to watch out for, and how to make safe, informed choices. The discussion covers why tooth discoloration often appears after orthodontic treatment, how microabrasion physically alters enamel, and the crucial role of fluoride in supporting remineralization. Dr. Rob also examines the limitations and pote...

Is your whitening toothpaste actually brightening your smile—or quietly wearing down your enamel?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami break down the science behind peroxide-based whitening toothpastes, diving into how hydrogen peroxide actually works to lift stains from teeth. Using popular products like Colgate Optic White Pro Series as examples, they explain the chemistry of stain removal, the role of pH, and how abrasiveness (measured by RDA) affects both whitening power and sensitivity. The conversation also explores the latest research on peroxide penetration, revealing why formulation is key to safety and...

Is nano hydroxyapatite really the natural alternative to fluoride—or just clever marketing dressed up as science?

In this episode of Dental Formulator's Playbook, Dr. Rob and Tami continue their deep dive into nano hydroxyapatite (nano HAP) toothpaste — this time taking an even closer look at the evidence, marketing, and regulatory gaps surrounding the trendy ingredient. They dissect the claims that nano HAP is a fluoride replacement, exposing research biases, weak studies, and misleading advertising tactics that have fueled the hype. Dr. Rob explains why fluoride is still the gold standard for enamel remineralization and stresses the impo...

Is nano hydroxyapatite the breakthrough your teeth have been waiting for—or just another viral myth in oral care?

In this episode of Dental Formulator's Playbook, Dr. Rob and Tami tackle the growing buzz around nano hydroxyapatite (nano HAP) — a trending ingredient in oral care products. They break down the science behind nano HAP, separating fact from fiction, and address viral claims that it can instantly repair or whiten teeth. Dr. Rob explains what remineralization really means, why fluoride remains the gold standard for enamel protection, and where nano HAP fits into the conversation. From potential use for...

Is LivFresh toothpaste a true innovation in oral care—or just another case of marketing hype outpacing the science?

In this episode of Dental Formulator's Playbook, Dr. Rob and Tami deliver an unfiltered review of LivFresh toothpaste, breaking down its bold marketing claims, questionable science, and patent assertions. From flashy promises to missing fundamentals, they examine what’s real, what’s exaggerated, and what consumers need to know. While some ingredients show potential, Dr. Rob explains why the product’s hype doesn’t match its scientific backing — and offers guidance on how to evaluate oral care claims more critica...

What really goes into making a safe, effective toothpaste or mouthwash—and who decides if it measures up?

In this episode of the Dental Formulator’s Playbook, Dr. Rob and Tami dive deep into the science and regulations behind toothpaste and mouthwash formulation. From FDA monographs and ADA approval to the complexities of ingredient selection and quality control, they break down what it really takes to bring an effective, safe, and compliant oral care product to market. Whether you're a formulator, brand owner, or curious consumer, this episode provides a behind-the-scenes look at the industry’s most critic...

Is water fluoridation a proven public health success—or a hidden risk for children and pregnant women?

In this episode of Dental Formulator’s Playbook, Dr. Rob and Tami the controversial topic of water fluoridation and its effects on health, particularly for pregnant women and children. They explore scientific studies related to fluoride exposure, analyze differences in fluoride levels from various sources, and explain how the human body regulates fluoride intake and excretion. The episode offers a measured, evidence-based look at one of the most hotly debated topics in public health.

Dr. Rob and Tami brea...

How did a mysterious case of mottled enamel in Colorado Springs spark the discovery that made fluoride the cornerstone of modern dentistry?

In this episode of Dental Formulator’s Playbook, Dr. Rob and his wife Tami explore the fascinating history and science behind fluoride as the gold standard in preventing tooth decay. They take listeners on a journey through early scientific discoveries, the implementation of water fluoridation, and the evolution of fluoride toothpaste. With a blend of storytelling and science, the episode highlights key breakthroughs, formulation challenges, and the significant impact fluoride has had on dental health ov...

How does a chemical physicist go from academic research to reinventing the science of oral care?

In this episode of the Dental Formulator’s Playbook, Dr. Rob, an independent scientist with a PhD in chemical physics, shares his unconventional journey into the oral care industry. He discusses his transition from academic research to developing innovative oral care products for both humans and animals, motivated by personal experience and scientific curiosity. Dr. Rob delves into the challenges of formulation science, regulatory hurdles, and the critical role of independent innovation. He also provides insights into product development, industry dynamics, an...