CCO Infectious Disease Podcast
By: Clinical Care Options
Language: en
Categories: Education, Courses, Science, Life, Health, Fitness
Weekly updates on new data and best practices in patient care for a variety of infectious diseases including COVID-19, HIV, and viral hepatitis, from Clinical Care Options. Gain practical strategies and earn CME/CE credit for selected episodes.
Episodes
Forging a Path Back to HIV Care
Oct 21, 2025In this episode, expert patient navigators Shellye Jones and Lauren Jackson discuss the key take-home points of our online educational program on facilitating engagement in HIV care and propose a framework for effectively retaining people in care. Topics covered include:
How to approach a patient with complex barriers to engagement in healthcareResources for staying in care, such as wraparound servicesSetting SMART goals and formulating action plans with patientsDeconstructing stigma and implementing a trauma-informed approach to carePresenters:
Shellye Jones, MSW, LCSW
Clinical Supervisor
Charles R. Drew University, Drew CARES
Los Angeles, California
Duration: 00:23:48
Overcoming Reluctance to Change as a Barrier to Optimizing ART for People Living With HIV and Viral Suppression
Oct 16, 2025Don’t settle! Listen in to learn how a proactive approach to ART switch can improve treatment satisfaction and quality of life for people living with virologically suppressed HIV. Topics covered include:
International AIDS Society (IAS) USA and European AIDS Clinical Society (EACS) Guidance on Switching ART With Viral SuppressionConsiderations for switching to a 2-drug regimen or long-acting ARTMethods for assessing patient satisfaction with their current ART regimenPresenters:
Monica Gandhi, MD, MPH
Director, UCSF-Bay Area Center for AIDS Research (CFAR)
Professor of Medicine and Associate Chief, Division of HIV, Infectious Diseases, and Gl...
HIV “Blips”: What They Are (and Aren’t)
Oct 08, 2025Detectable HIV-1 RNA (viral load) can seem very worrisome for people living with HIV who are receiving antiretroviral therapy (ART) and for their healthcare professionals. Tune in to learn how Brian R. Wood, MD, differentiates HIV-1 RNA “blips” from persistent low-level viremia and from virologic failure, and how he handles each scenario.
Presenter:
Brian R. Wood, MD
Professor of Medicine
Division of Allergy and Infectious Diseases
University of Washington
Seattle, Washington
Link to full program:
https://bit.ly/4nS7rYE
Get access to all of our new po...
Duration: 00:25:36Individualizing Care for Treatment-Experienced People With HIV
Sep 26, 2025Tune into this podcast from Dr Clíona Ní Cheallaigh to learn how to provide person-centered care for treatment-experienced people with HIV. Gain strategies to address each individual’s specific history and needs while considering the potential impact of comorbidities and other health challenges. Topics covered include:
Individualizing Antiretroviral Regimens for Treatment-Experienced People With HIVStrategies to Improve Adherence and Addressing Barriers to Engagement in CarePerson-Centered, Trauma-Informed CareResistance Testing in the Setting of Virologic FailureSelection of ARVs With a Failing RegimenPresenters:
Clíona Ní Cheallaigh, MB, MRCP, PhD
Consultant Physician
Inclusion Health Services
St Jam...
Clinical Scenarios Podcast: A Deep Dive Into Refractory CMV Infections
Sep 03, 2025In this podcast, expert faculty Atul Humar, MD, FRCP (C), and Camille Kotton, MD, FIDSA, FAST, take a deep dive into complex clinical scenarios and explore designing antiviral regimens for refractory CMV infections to minimize antiviral toxicities and maximize efficacy. Topics covered include:
Management for suspected drug-resistant CMV infection Illustrative patient cases Gene mutations in CMV
Presenters:
Atul Humar, MD, FRCPC, FAST
Professor
Department of Medicine
University of Toronto
Eaton Family Chair in Transplant Infectious Diseases
Ajmera Transplant Centre
University Health Network
Toronto, Canada
Cami...
Duration: 00:17:04Charting the Course Podcast: Antivirals for Refractory CMV Infections
Aug 29, 2025Learn to appropriately modify antiviral therapy in solid organ transplant recipients with treatment-refractory cytomegalovirus (CMV) infections with expert faculty, Atul Humar, MD, FRCP (C). Topics covered include:
Comparisons of available CMV antiviral therapies:Ganciclovir, valganciclovir, foscarnet, cidofovir, maribavirConsiderations for renal function monitoring with ganciclovir and valganciclovirA treatment algorithm for relapsed/refractory CMVThe latest clinical trial data and guideline recommendationsPresenter:
Atul Humar, MD, FRCP (C)
Professor
Department of Medicine
University of Toronto
Eaton Family Chair in Transplant Infectious Diseases
Ajmera Transplant Centre
University Health Network
Toronto, Canada
L...
Duration: 00:18:40Soundings Podcast: Identifying Refractory CMV Infections in Transplant Settings
Aug 29, 2025Tune in to learn the fundamentals for timely identification of refractory cytomegalovirus (CMV) infections following solid organ transplantation from expert faculty, Camille Kotton, MD, FIDSA, FAST. Topics covered include:
Direct and indirect effects of CMV infectionRisk factors for resistant/refractory CMVDefining resistant/refractory CMVPresenter:
Camille Kotton, MD, FIDSA, FAST
Clinical Director, Transplant and Immunocompromised Host Infectious Diseases
Infectious Diseases Division
Mass General Brigham Endowed Cancer Chair IV
Massachusetts General Hospital
Associate Professor, Harvard Medical School
Boston, Massachusetts
Link to full program:
http://bit.ly/4lOa2kA
Duration: 00:11:53
The Patient Angle: Individualized Approaches for Managing CMV
Aug 26, 2025Listen in as Dr Marcus Pereira and Dr Raymund R. Razonable explore strategies for individualization of CMV management in high-risk kidney transplant recipients. Topics include:
Risk factors and prevention of late-onset CMV diseaseEarly detection of late CMV infectionCMV cell-mediated immunity monitoringPrimary and secondary prophylaxis
Presenters:
Marcus Pereira, MD, MPH, FAST
Associate Professor of Medicine
Director of Clinical Services, Division of Infectious Diseases
Medical Director, Transplant Infectious Disease Program
Columbia University Irving Medical Center
New York, New York
Raymund R. Razonable, MD, FIDSA, FAST
Professor of Medicine
The Viral Angle: CMV in Kidney Transplantation
Aug 26, 2025Listen in as Dr Marcus Pereira and Dr Raymund R. Razonable discuss the fundamentals of cytomegalovirus (CMV) in kidney transplant recipients. Topics include:
CMV pathogenesisDirect and indirect effects of CMV infection Overview of patient risk factorsCMV risk based on serologic status
Presenters:
Marcus Pereira, MD, MPH, FAST
Associate Professor of Medicine
Director of Clinical Services, Division of Infectious Diseases
Medical Director, Transplant Infectious Disease Program
Columbia University Irving Medical Center
New York, New York
Raymund R. Razonable, MD, FIDSA, FAST
Professor of Medicine
Division of Infectiou...
Syndromic Testing Podcast: Gastrointestinal and Joint Infections
Aug 26, 2025Listen in as Dr Trevor Van Schooneveld explores rapid syndromic testing for gastrointestinal and joint infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.
Topics covered include:
Who should be tested for infectious diarrheaTypes of gastrointestinal syndromic panelsTypes of syndromic panels for joint infectionsReal-world applications for joint syndromic panelsPresenters:
Trevor Van Schooneveld, MD
Professor, Division of Infectious Diseases
Medical Director, Antimicrobial Stewardship Program
Department of Internal Medicine
University of Nebraska Medical Center
Omaha, Nebraska
Link to full program:
The Antiviral Angle: Leveraging the Full CMV Armamentarium
Aug 26, 2025Listen in as Dr Marcus Pereira discusses how to design cytomegalovirus (CMV) antiviral regimens for high-risk kidney transplant recipients to mitigate the impact of infection while minimizing drug toxicities. Topics include:
Strategies for CMV prevention: prophylaxis, preemptive therapy, and hybrid methodsCharacteristics of available antiviral drugsMonitoring considerations for antiviralsPresenters:
Marcus Pereira, MD, MPH, FAST
Associate Professor of Medicine
Director of Clinical Services, Division of Infectious Diseases
Medical Director, Transplant Infectious Disease Program
Columbia University Irving Medical Center
New York, New York
Link to full program:
http://bit.ly/41ejruC...
Heartbreak to Hope: My Journey With Meningitis Vaccine Advocacy
Aug 25, 2025Join Alicia Stillman of the American Society for Meningitis Prevention, as she shares a very personal story of loss that might change how you view meningitis vaccination.
Presenter:
Alicia Stillman, MBA, MPH
Patient Advocate
Co-Executive Director, American Society for Meningitis Prevention
Executive Director, Emily Stillman Foundation
Detroit, Michigan
Link to full program:
https://bit.ly/4mYvTXQ
Register for the practical symposium:
https://bit.ly/4mUOsvV
Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple...
Duration: 00:07:23Syndromic Testing Podcast: Respiratory Infections
Aug 19, 2025Listen in as Michael Satlin, MD, MS, FIDSA,explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.
Topics covered include:
Types of upper and lower respiratory infection panelsConsiderations for when to use respiratory syndromic testingHow to use syndromic testing to guide both therapy escalation and de-escalationHow syndromic testing fits in with traditional testing methods, such as culture, antimicrobial susceptibility testing, Gram stain, and BAL cell countPresenter:
Michael Satlin, MD, MS, FIDSA
Associate Professor of Medicine and Pathology and L...
Advancing HIV Treatment: Leveraging Pharmacists’ Expertise
Aug 18, 2025Stream this podcast to learn from experts Alexis E. Horace, PharmD, BCACP,andNimish Patel, PharmD, PhD, AAHIVP, how specialist pharmacists can overcome key barriers to care and apply best practices for optimization of antiretroviral therapy for HIV. Topics covered include:
Leveraging pharmacists’ expertise to advance HIV treatmentPharmacist roles in HIV care and management The current ART landscapeRegimen simplificationConsideration of patient preferences, health factors, and comorbidities for ART optimizationART management for treatment-experienced patients, including those with multidrug-resistant HIVPresenters:
Alexis E. Horace, PharmD, BCACP
Professor of Pharmacy Practice
University of Louisiana at Monroe College of Ph...
Lenacapavir Approval: What to Know When Selecting a PrEP Regimen
Aug 13, 2025Tune in to learn how the recent FDA approval of lenacapavir (LEN) for PreP integrates into the current field of HIV prevention. Listen on the go or follow along with our expert-curated slides. Topics covered include:
The current landscape of PrEPFDA approval of lenacapavirPhase III efficacy and safety data for lenacapavirRecommendations and perspectives on the future of PrEPPresenters:
Colleen F. Kelley, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Co-Director, Emory Center for
AIDS Research
Associated Dean for Research,
Emory at Grady
Emo...
Key HIV Studies Influencing My Practice Following IAS 2025—Dr Beatriz Grinsztejn and Rosie Mngqibisa
Aug 12, 2025Hear from experts in HIV care Beatriz Grinsztejn, MD, PhD, and Rosie Mnggibisa, MBChB, MPH, as they discuss their insights on some of the most clinically relevant new data presented at IAS 2025, including studies on:
Gaps in care for adolescents and young adults living with HIVGlobal impact of funding cutsAntiretroviral therapy for treating HIVPatient management strategies for people living with HIV and obesityPresenters:
Beatriz Grinsztejn, MD, PhD
Director
STI/HIV Clinical Research Laboratory
Evandro Chagas National Institute of Infectious Diseases – FIOCRUZ
Rio de Janeiro, Brazil
Rosie Mngqibisa, MBChB, MPH...
Duration: 00:43:36Syndromic Testing Podcast: Bloodstream Infections
Aug 12, 2025Listen in as Dr Emily Heil explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing.
Topics covered include:
The importance of good blood culture practices and finding the balance between overuse and underuseBlood culture improvement programsThe utility of rapid diagnostic testsResistance markers for earlier targeted therapyPresenters:
Emily Heil, PharmD, MS, BCIDP, AAHIVP
Professor
Department of Practice, Sciences, and Health Outcomes Research
University of Maryland School of Pharmacy
Baltimore, Maryland
Link to full program:
Fundamentals on Integrating Specialized Agents for Treatment-Experienced People With HIV
Aug 11, 2025Tune in as Dr George Behrenspresents the fundamentals on specialized agents for treatment-experienced people living with HIV.
Topics covered include:
Key targets and mechanisms of action for specialized HIV drugsClinical trial data supporting safety and efficacy of these agentsConsiderations for potential drug–drug interactions Strategies for leveraging these agents to construct new ART regimens for treatment-experienced individualsPresenters:
Georg Behrens, MD
Professor of Immunology
Senior Consultant
Department of Rheumatology and Immunology
Hannover Medical School, Germany
Hannover, Germany
Link to full program:
https://bit.ly/4oiYxEx
G...
Duration: 00:23:09Essentials for ART Selection for Treatment-Experienced People With HIV and Comorbidities
Aug 08, 2025In this episode, Dr Josep M. Llibrereviews the essentials on ART selection for treatment-experienced people with HIV and comorbidities.
Topics covered include:
Underlying reasons for development of multidrug-resistant HIVInflammation and immune activation associated with frequency of age-related conditions General principles for designing ART regimens for persons with multidrug-resistant HIVTreatment options for highly treatment‒experienced peopleConsiderations for comorbidities and drug–drug interactionsPresenters:
Josep M. Llibre, MD, PhD
Senior Consultant
Infectious Diseases Division
Fight Infections Foundation
University Hospital Germans Trias
Badalona, Barcelona, Spain
Link to full program:
ht...
Key Principles for Getting Started With Managing Multidrug-Resistant HIV
Aug 05, 2025Tune in as Dr Daniel R. Kuritzkes presents a quick and easy primer on managing multidrug resistant HIV.
Topics covered include:
How to recognize key populations who may present with multidrug-resistant HIVIdentifying underlying reasons for regimen failureEvaluating resistance profilesConstructing new ART regimens for treatment-experienced individuals.Presenters:
Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women's Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts
Link to full program:
https://bit.ly/4oiYxEx
Get access to all of ou...
Duration: 00:09:39Key PBC Studies From EASL and DDW 2025
Jul 07, 2025In this episode, Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH, discusses the most recent developments in primary biliary cholangitis (PBC) treatment, including cutting-edge data on new and emerging agents and how these updates may be integrated into your practice. Topics include:
Steatotic liver disease and PBCVibration-controlled transient elastography (VCTE) and discordant biochemical responses in PBCPPAR agonists and IBATs for PBC treatment
Presenter:
Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH
Associate Professor
NIHR Birmingham BRC
University of Birmingham
Consultant Hepatologist, Liver Unit
University Hospitals Birmingham
Birmingham, United...
Expert Insights for Transforming Your Practice Into a Vaccine Center of Excellence
Jun 30, 2025Listen as expert faculty answer your most pressing questions on optimizing immunization in clinical practice.
Topics covered include:
Practical methods for improving confidence in vaccinesHow to educate patients on vaccine development and safety monitoring Effective strategies to tailor recommendations, such as motivational interviewingWays to navigate clinical encounters and address vaccine hesitancyPresenters:
Robert H. Hopkins, Jr., MD, MACP
Professor of Internal Medicine and Pediatrics
University of Arkansas for Medical Sciences
College of Medicine
Little Rock, Arkansas
Litjen (L.J.) Tan, MS, PhD
Chief Policy and Partnership Office, I...
Partnering With Patients for PBC Care: Actionable Strategies for HCPs
Jun 26, 2025In this episode, Dr Gideon Hirschfield meets with patient advocate Jess Schnur to discuss challenges related to the diagnosis and management of primary biliary cholangitis (PBC) to provide actionable strategies for healthcare professionals to incorporate into patient care, including:
Disease concerns and frequently asked questions from a patient perspectiveManaging symptomsTreatment options and supportive careImportance of awareness and educationPresenters:
Gideon Hirschfield, MA, MB BChir, FRCP, PhD
Lily and Terry Horner Chair in Autoimmune Liver Disease Research
Professor, Division of Gastroenterology and Hepatology
University of Toronto
Director, The Autoimmune and Rare Liver Disease...
PBC Perspectives: A Patient and HCP in Conversation
Jun 26, 2025In this podcast, Sonal Kumar, MD, MPH, meets with patient advocate Maria Morais to discuss actionable steps that healthcare providers can incorporate into the care of people with primary biliary cholangitis (PBC). Listen as they discuss:
The chronic nature of PBCGoing beyond biochemical markers to assess and address symptoms such as fatigue and pruritusThe importance of referral to patient support groupsPresenters:
Sonal Kumar, MD, MPH
Assistant Professor of Medicine
Director, General Gastroenterology and Hepatology
Weill Cornell Medical College
New York, New York
Maria G. Morais, RN
VP...
Debating the Role of ALP Normalization in PBC: Curbside Consults Podcast
Jun 26, 2025In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau, use an illustrative patient case to explore the roles of ALP and other biochemical markers in PBC management, and explain what to expect from treatment. Topics covered include:
How baseline ALP can affect ALP normalization after second-line treatment with elafibranor and seladelparPotential outcomes if ALP normalization cannot be achievedThe importance of managing fatigue, pruritus, and sleep disturbances independently of the biochemical responsePresenters:
Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Managing PBC Therapy for Patients With Cirrhosis: Curbside Consults Podcast
Jun 26, 2025In this podcast, expert faculty, Dr Stuart Gordon and Dr Nancy Reau discuss an illustrative patient case to demonstrate how they individualize primary biliary cholangitis (PBC) therapy for patients with cirrhosis. Topics covered include:
AASLD guideline recommendations for second-line therapy for PBCConsiderations when using newer agents for second-line treatment of PBC in patients with cirrhosis: elafibranor and seladelparPresenters:
Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan
Nancy Reau, MD
Professor of Medicine
...
Innovations in NCFBE: Understanding the Patient Burden and Best Practices in Diagnostics
Jun 18, 2025In this podcast, Brett M. Elicker, MD, and David E. Griffith, MD, ATSF, FACCP, FRSM, discuss the pathophysiology of non–cystic fibrosis bronchiectasis (NCFBE), the patient burden, and best practices with diagnosing NCFBE, including:
The vicious vortex of NCFBE (ie, airway dysfunction, inflammation, infection)Cough as the most significant symptom and burdenImaging bronchiectasis with classic and inflammatory findingsDifferentiating the causes of NCFBE to inform patient carePresenters
Brett M. Elicker, MD
Professor of Clinical Radiology
Chief, Cardiothoracic Imaging Division
Department of Radiology & Biomedical Imaging
University of California, San Francisco
San Fr...
Evaluating and Managing PBC Symptoms: Curbside Consults Podcast
Jun 18, 2025In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss how they assess the symptoms of primary biliary cholangitis (PBC) and explore how new therapeutic agents may help alleviate symptom burden. Topics include:
Strategies and tools for assessing pruritusNonpharmacologic and pharmacologic management of pruritusSecond-line agents and their impact on pruritusInvestigational treatments for pruritusPresenters:
Alan Bonder, MD, AGAF
Associate Professor of Medicine
Medical Director of Liver Transplant
Department of Gastroenterology
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts
Aparna Goel...
Duration: 00:18:43Defining Nonresponse to PBC Treatment: Curbside Consults Podcast
Jun 18, 2025How do you decide when to move from first-line to second-line treatment for primary biliary cholangitis (PBC)? In this podcast, listen as experts Alan Bonder, MD, AGAF, and Aparna Goel, MD, discuss this question and more, including:
How and when to measure treatment responseEvidence-based goals of therapyConsiderations for second-line treatmentNew agents for second-line treatment: PPAR agonistsPresenters:
Alan Bonder, MD, AGAF
Associate Professor of Medicine
Medical Director of Liver Transplant
Department of Gastroenterology
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts
Aparna Goel, MD
...
Listen Up: Time to Prioritize RSV Vaccination for Adults
Jun 11, 2025Respiratory Syncytial Virus (RSV) significantly impacts adults, especially those over age 60 and those with chronic conditions.
In this podcast, nurse practitioners Drs. Carrico and Stevenson discuss the underestimated burden of RSV. The podcast also explores practical strategies for increasing vaccine uptake that you can apply to your practice starting today so that you can protect your patients against RSV.
Listen as they discuss:
The Burden of Adult RSVRSV Vaccines for Adults: Data and RecommendationsRSV Vaccine UptakePractical Strategies to Increase RSV Vaccine UptakeFaculty:
Dr. Ruth Carrico is a family nurse pr...
Duration: 01:06:50Paving the Way: Overcoming Barriers to RSV Vaccination
Jun 02, 2025Listen in as Carolyn Bridges, MD, FACP, and Laura P. Hurley, MD, MPH, discuss barriers to respiratory syncytial virus (RSV) vaccination for adults, including insurance coverage and vaccine hesitancy, and explore effective, practical strategies for overcoming these barriers. Topics covered include:
Helping patients understand why they need an RSV vaccineWays to discuss real-world vaccine efficacyApproaches to build vaccine confidence and discuss vaccine safetyMethods to overcome financial barriers and time constraintsVaccine delivery infrastructurePresenters:
Carolyn Bridges, MD, FACP
Consulting Physician and Director of Adult Immunizations
Immunize.org
St Paul, Minnesota
Laura...
Duration: 00:25:46The Latest Data and Guidelines for Adult RSV Vaccines
Jun 02, 2025Listen in as Carolyn Bridges, MD, FACP, reviews the estimated burden of respiratory syncytial virus (RSV) disease in older adults and discusses the latest updates on RSV vaccination recommendations and safety data. Topics covered include:
Rates of RSV hospitalizations and emergency department visitsRSV vaccine developmentFDA-approved RSV vaccinesVaccine safety data: rates of atrial fibrillation and Guillain-Barré syndromeACIP RSV vaccine recommendationsRisk factors for severe RSV diseaseRSV vaccine uptakePresenter:
Carolyn Bridges, MD, FACP
Consulting Physician and Director of Adult Immunizations
Immunize.org
St Paul, Minnesota
Link to full program:
https://bit.ly/4mH...
Overcoming Common Hurdles to RSV Vaccination in Post-acute and Long-term Care
Apr 10, 2025In this episode, Jewel Mullen, MD, MPH, MPA, and Dallas Nelson, MD, CMD, FACP discuss overcoming barriers to RSV vaccine uptake in post-acute and long-term care facilities, including:
How to incorporate the latest RSV vaccination recommendations into clinical practicePractical strategies for navigating insuranceEffective and empathetic methods of addressing vaccine hesitancy.
Presenters:
Jewel Mullen, MD, MPH, MPA
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Austin, Texas
Dallas Nelson, MD, CMD, FACP
Professor of Medic...
Key HIV Studies Influencing My Practice Following CROI 2025—Dr Chloe Orkin and Dr Jean-Michel Molina
Apr 04, 2025In this episode, Chloe Orkin, MBChB, FRCP, MD, and Jean-Michel Molina, MD, PhD, discuss highlights from CCO’s independent conference coverage of CROI 2025, including:
Advances in HIV treatment based on results from CARESPotential HIV therapies in the pipeline, such as doravirine/islatravirEffects of broadly neutralizing antibodies on HIV treatment and cure Key clinical data on HIV and STI prevention obtained from PILLAR, HPTN 083, PURPOSE 1, and STOMPPresenters:
Chloe Orkin, MBChB, FRCP, MD
Professor of Infection and Inequities
Dean for Healthcare Transformation
Honorary Consultant Physician, Barts Health NHS Trust
Faculty of Medicine and Den...
COVID-19 in EU: Inpatient Treatment Options for Severe COVID-19 in People Who Are Immunocompromised
Mar 13, 2025Listen in as Cristina Mussini, MD; Martin Witzenrath, MD, FERS; and Michele Bartoletti, MD, PhD, discuss treatment strategies for people who are immunocompromised with COVID-19 in the hospital setting, including:
Antiviral therapy with remdesivirDexamethasone for patients with hematologic malignanciesConsiderations regarding other immunomodulators such as JAK inhibitors or IL-6 inhibitorsA detailed patient case to illustrate key takeaways
Presenters:
Michele Bartoletti, MD, PhD
Associate Professor of Infectious Diseases
Department of Biomedical Sciences
Humanitas University
Pieve Emanuele (MI), Italy
Head of Infectious Diseases Unit
IRCCS Humanitas Research Hospital
Rozzano (MI...
Treatment Options for Severe COVID-19 in Patients Who Are Immunocompromised
Mar 10, 2025In this episode, Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss treatment strategies for people who have severe COVID-19, including:
Antiviral therapy with remdesivir Dexamethasone and other systemic corticosteroids Immunomodulators, such as JAK inhibitors or IL-6 inhibitors Overviews of clinical trial data demonstrating how and when to use these therapies
Presenters:
Stephen Cantrill, MD, FACEP
Associate Director and Medical Director (Retired)
Department of Emergency Medicine
Denver Health Medical Center
Associate Professor
Department of Emergency Medicine
University of Colorado Health Sciences Center
Denver...
Simplifying HBV Screening and Care: Paths to Elimination
Mar 10, 2025In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss practical strategies to overcome barriers to hepatitis B virus (HBV) care, including:
Overcoming health insurance navigation Improving access to HBV care in immigrant communitiesDispelling HBV myths and stigmaSolutions to language barriersCommunity-based interventions
Presenters:
Patricia D. Jones, MD, MSCR
Associate Professor of Clinical Medicine
Director of Clinical Operations-Hepatology
Division of Digestive Health and Liver Diseases
Department of Medicine
University of Miami Miller School of Medicine
Sy...
Best Practices for Inpatient Management of Severe COVID-19
Mar 10, 2025In this episode, Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss:
Workup of COVID-19 in the emergency departmentMethods of COVID-19 risk stratification Treatment recommendations for people with severe COVID-19, including how to effectively use antiviral therapy, dexamethasone, and other immunomodulators[CC1] in this population A detailed patient case to illustrate key takeaways
Presenters:
Stephen Cantrill, MD, FACEP
Associate Director and Medical Director (Retired)
Department of Emergency Medicine
Denver Health Medical Center
Associate Professor
Department of Emergency Medicine
University of Colorado Health Sciences Cent...
COVID-19 in the EU: Inpatient Treatment of Mild to Moderate COVID-19 in Patients Who Are Immunocompromised
Feb 06, 2025In this episode, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss the management of mild to moderate COVID-19 in patients who are immunocompromised, including:
Initial workup, which may include laboratory tests and/or imagingLatest data on the use of remdesivir or nirmatrelvir plus ritonavir for mild to moderate COVID-19, including considerations for drug–drug interactions
Presenters:
Martin Witzenrath, MD, FERS
Medical Director
Charite Centrum 12
Internal Medicine & Dermatology
Professor and Chair for Respiratory Medicine and Critical Care
Department of Infectious Disease, Respiratory Medicine and Critical Care
Cha...
Defining Best Practices in HBV Care
Feb 05, 2025In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss best practices in hepatitis B virus (HBV) care, including:
2023 CDC HBV screening recommendationsSummary of guideline recommendations for hepatitis delta virus (HDV) screening Use of HDV reflex testing to avoid loss to follow-up2024 WHO HBV treatment recommendations, including recommendations for pregnant persons
Presenters:
Patricia D. Jones, MD, MSCR
Associate Professor of Clinical Medicine
Director of Clinical Operations-Hepatology
Division of Digestive Health and Liver Diseases
Department of Med...
COVID-19 in the EU: Current Trends and Risk Factors for Severe COVID-19 Progression
Feb 05, 2025In this episode, Cristina Mussini, MD, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss:
Current SARS-CoV-2 trends in the EURisk factors for severe COVID-19 outcomes, including the spectrum of risk based on immune system statusFactors that may affect vaccine efficacy in chronic lymphocytic leukemia and other lymphoid malignanciesConsiderations for determining people at high risk for COVID-19 progression
Presenters:
Cristina Mussini, MD
Full Professor of Infectious Diseases
Division of Infectious Diseases
University of Modena and Reggio Emilia
Modena, Italy
Martin Witzenrath, MD, FERS
Medical Director
Simplified HCV Care in Sexual and Reproductive Health Clinics
Jan 08, 2025In this episode, Tzu-Hao (Howard) Lee, MD; Tatyana Kushner, MD, MSCE; and patient advocate Andrew Reynolds discuss hepatitis C virus (HCV) care in men who have sex with men and pregnant people, including:
HCV disease burden in the United StatesScreening recommendations Strategies to overcome barriers to HCV screeningTreatment recommendations, including simplified treatment guidance and considerations for pregnant peopleStrategies to improve treatment uptake
Presenters:
Tzu-Hao (Howard) Lee, MD
Assistant Professor
Section of Gastroenterology and Hepatology, Department of Medicine
Division of Abdominal Transplant, Department of Surgery
Baylor College of Medicine
Houston, T...
Key PBC Studies From AASLD 2024
Jan 07, 2025In this episode, Sonal Kumar, MD, MPH, discusses key findings from primary biliary cholangitis (PBC) studies presented at AASLD 2024, including:
ELATIVE, a phase III trial of elafibranor for PBCRESPONSE, a phase III trial of seladelpar for PBCASSURE, another phase III trial of seladelpar for PBCPresenter:
Sonal Kumar, MD, MPH
Director, Clinical Gastroenterology and Hepatology
Assistant Professor of Medicine
Weill Cornell Medical College
New York, New York
Link to full program:
https://bit.ly/41tvSDu
Get access to all of our new podcasts by subscribing to the C...
Duration: 00:20:16Understanding Current Trends and Risk Factors for Progression to Severe COVID-19
Jan 02, 2025Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss current trends in and risk factors for progression to severe COVID-19, including for those for whom COVID-19 is not their primary concern when presenting to the emergency department (ED). Key topics of discussion include:
How to complete a comprehensive patient workup in the EDConsiderations regarding pulse oximetryRisk stratification—what places patients at higher risk of severe disease?A detailed patient case to illustrate key takeawaysPresenters:
Stephen Cantrill, MD, FACEP
Associate Director and Medical Director (Retir...
Simplified HCV Screening and Care in People Who Use Drugs
Dec 23, 2024In this episode, Stacey B. Trooskin, MD, PhD, MPH, Mark S. Sulkowski, MD, FIDSA, FAASLD, and Ronni Marks discuss hepatitis C virus (HCV) screening and treatment, focusing on people who use drugs, and highlight the following topics:
Screening recommendationsStrategies to improve HCV screeningHCV testingTreatment goalsStrategies to improve HCV treatment uptakePresenters:
Stacey B. Trooskin, MD, PhD, MPH
Executive Medical Officer
Mazzoni Center
Faculty, University of Pennsylvania
Perelman School of Medicine
Philadelphia, Pennsylvania
Mark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases...
Inpatient Treatment for Mild to Moderate COVID-19
Dec 19, 2024Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss best practices in treating patients hospitalized with mild to moderate COVID-19, including:
Current guidelines from the Infectious Diseases Society of America and National Institutes of Health How to optimize therapy selection based on patient risk factors, including key data supporting best practicesA detailed patient case to illustrate key takeawaysPresenters:
Stephen Cantrill, MD, FACEP
Associate Director and Medical Director (Retired)
Department of Emergency Medicine
Denver Health Medical Center
Associate Professor
Department of Emergency...
Emerging Therapies for Pruritus in PBC
Dec 18, 2024Clinical gaps in the treatment of pruritus in primary biliary cholangitis (PBC) remain. In this episode, taken from a recent symposium, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss emerging therapies currently in clinical trials for the management of this disease that can dramatically affect patients’ quality of life.
Listen as they discuss:
Gaps in current managementPatient perspectives: why we should not dismiss itching as an underlying psychologic problemPPAR agonists and how they affect pruritusBEZURSO and FITCH ELATIVEENHANCE and RESPONSEIBATs (inhibitors of bile acid transport)GLIMMERCommon que... Duration: 00:23:34Clinical Management of Pruritus in PBC
Dec 18, 2024Although there is currently no FDA-approved treatment for pruritus in primary biliary cholangitis (PBC), symptoms can be mitigated with nonpharmacologic or pharmacologic agents. In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss the clinical management of pruritus in PBC, including:
Pruritus assessment toolsOptimal use of tools, including frequency of assessmentCurrent management of pruritusNonpharmacologic interventionsPharmacologic agentsStrategies to optimize assessment and management of pruritusCollaborative careDevelopment of a treatment planOngoing assessment and adjustment of therapyResources and support for patientsPresenters:
Marlyn J. Mayo, MD
Professor...
Living With Pruritus in PBC: A Patient Perspective
Dec 18, 2024In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with primary biliary cholangitis (PBC), discuss the burden of pruritus in PBC and the impact it has on quality of life, including both physical and mental health, from a patient’s perspective.
Presenters:
Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, Texas
Stuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of He...
CCO Independent Conference Coverage of IDWeek and Glasgow 2024
Dec 17, 2024In this episode, Jean-Michel Molina, MD, PhD, and Joseph J. Eron, Jr., MD, discuss results from key clinical trials on HIV prevention and treatment as well as sexually transmitted infection (STI) prevention presented at IDWeek and Glasgow 2024, including:
PURPOSE 1 and 2 comparing lenacapavir injection vs oral TDF/FTCTRIO Health Cohort and OPERA examining long-acting cabotegravir as PrEPDOLCE comparing DTG/3TC as first-line therapy in treatment-naive patients with HIVPRIDOX evaluating the use of DoxyPEP on STI incidence in men who have sex with men on PrEP
Presenters:
Jean-Michel Molina, MD, PhD
Professor of Infectious Diseases<...
Recent Advances in PBC Management
Dec 13, 2024In this episode, Christopher L. Bowlus, MD, discusses recent advances in the management of primary biliary cholangitis (PBC), including:
Treatment goalsUse of PPAR agonists for the treatment of PBCClinical trial results for elafibranor (ELATIVE), seladelpar (RESPONSE), and bezafibrate (BEZURSO)Presenter:
Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
University of California Davis School of Medicine
Sacramento, California
Link to full program:
https://bit.ly/41tvSDu
Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Pod...
Duration: 00:08:46Be an Ally: Navigating the Healthcare System as a Transgender Individual With HIV
Nov 13, 2024In this episode, a transfemme nonbinary individual living with HIV shares her experience navigating the healthcare system, alongside her infectious disease physician, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS. Hear them discuss key considerations when caring for gender-diverse individuals, including:
Understanding how people are more than just a diagnosis Prioritizing individuals’ needs and providing whole-person care using shared decision-makingStrategies to make an environment more affirming and welcoming How to be an ally to transgender individualsListen to the individual in front of youHear what they’re telling youMake sure they are being affirmed and seenLink to the full pr...
Duration: 00:32:05Key HIV Studies Influencing My Practice Following HIVR4P 2024—Drs . Linda-Gail Bekker and Meredith Clement
Oct 30, 2024In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:
Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudyImplementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health ClinicsImproving PrEP uptake based on results from SPrEP and HPTN 091Presenters:
Meredith E. Clement, MD
Associate Professor
Be an HPV Vaccine Champion: Reaching Underserved Populations
Oct 29, 2024Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to achieve health equity in HPV vaccination, including:
Trends among males vs femalesMessaging considerations for those from diverse populations (eg, LGTBQ+ and rural communities)How healthcare professionals can address barriers to careThen, hear answers from the experts to frequently asked questions regarding HPV vaccination recommendations, timing, and example case studies.
Presenters:
Rebekah Fenton, MD, MPH
Adolescent Medicine Physician
Alivio Medical Center
Chicago, Illinois
Sharon G. Humiston, MD, MPH
Director for Research
Key HIV Studies Influencing My Practice Following HIVR4P 2024—Drs . Linda-Gail Bekker and Meredith Clement
Oct 28, 2024In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:
Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudyImplementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health ClinicsImproving PrEP uptake based on results from SPrEP and HPTN 091
Presenters:
Meredith E. Clement, MD
Associate Professor
Strategies to Improve HPV Vaccine Uptake: Effective Vaccine Messaging
Oct 28, 2024Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to improve your messaging techniques with the HPV vaccine, including:
Persisting in vaccine recommendation after initial refusalEducating patients and their families togetherEnsuring staff are trained to correctly answer questionsKnowing when interested patients in your state can consent to vaccination without needing parental consentPresenters:
Rebekah Fenton, MD, MPH
Adolescent Medicine Physician
Alivio Medical Center
Chicago, Illinois
Sharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New Y...
The True Burden of HPV Infection
Oct 28, 2024Listen in as Sharon G. Humiston, MD, MPH, discusses current trends in HPV, including:
Incidence and prevalence trends in the USSex-related features of HPV-attributable cancersHow HPV vaccination uptake can prevent certain types of cancerCurrent guidelines and recommendations for HPV vaccinationPresenter:
Sharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New York
To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
Follow along with the slides:
https://bit.ly/4flD...
Making Addiction Care an Integral Part of HIV Care
Oct 08, 2024In this episode, Kathleen Page, MD, and Glenn J. Treisman, MD, PhD, discuss the interplay between addiction and HIV. Learn as they share their approaches to reframing the conversation about addiction and overcoming barriers to effective addiction care for people living with HIV.
Presenters:
Kathleen Page, MD
Professor
Infectious Diseases
Johns Hopkins School of Medicine
Baltimore, Maryland
Glenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland
Downloadable slides:
https://b...
Persisting in HIV Care: Considerations for People With Substance Use Disorders
Sep 13, 2024In this episode, Alexander Wong, MD, FRCPC, discusses how to optimize treatment and engagement in care for individuals with HIV and substance use disorder, including:
Barriers to care for persons with substance use disorder Colocating HIV and other services (eg, addiction care medicine, social services) Leveraging a multidisciplinary approach to care Integrating a low-barrier model to foster an environment of open discussion Best practices for opioid agonist therapy implementationConsiderations for cultural dynamics to provide personalized treatment plansImportance of supporting his team membersPresenter
Alexander Wong, MD, FRCPC
Associate Professor
Division of Infectious Diseases
D...
Integrating New Data From AIDS 2024: Pharmacist Perspectives
Aug 30, 2024In this episode, Jennifer Cocohoba, PharmD, AAHIVP, and David Koren, PharmD, MPH, AAHIVP, FIDSA, cover the most impactful LA ART and LA PrEP clinical studies presented at AIDS 2024, including:
The PURPOSE 1 study of twice-yearly lenacapavir injections vs daily oral tenofovir as PrEP in cisgender womenAn open-label extension of HPTN 084 evaluating LA CAB safety during pregnancy48-week data from the IMPAACT 2017/MOCHA study of LA CAB + RPV in adolescents with HIVA substudy of FLAIR evaluating the efficacy, safety, and tolerability of SC self-administration of LA CAB + RPVPresenters:
Jennifer Cocohoba, PharmD, AAHIVP
Professor of C...
How to Make PTSD and Trauma Care an Integral Part of HIV Care
Aug 27, 2024In this episode, Tristan J. Barber, MA, MD, FRCP, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating PTSD in people with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, sharing their own experiences and approaches to thinking about PTSD, structuring appointments, and integrating care.
Presenters:
Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Royal Free London NHS Foundation Trust
Honorary Associate Professor
Institute for Global Health
University College London
London, United Kingdom
G...
Duration: 00:38:27Be an Ally: How to Improve Care for Transgender Persons Living With HIV
Aug 22, 2024In this episode, Colleen F. Kelley, MD, MPH, and Jemma Samitpol discuss key considerations to improve the patient experience among transgender persons with HIV, including:
Unique circumstances faced by transgender people trying to access HIV care (eg, stigma, discrimination)Best practices to improve access and linkage to HIV careWays to integrate gender-affirming care into HIV careCreating a welcoming and inclusive environmentOffering same-day HIV treatmentAddressing potential drug–drug interactions with gender-affirming hormone therapy (GAHT), including ART and natural remediesUnderstanding and communicating expectations of GAHT (eg, treatment response, timing of effects)Providing information on the safety of gender-affirming surgeriesImportance of prov... Duration: 00:37:21Considering Long-acting ART With Viremia and Past Adherence Challenges
Aug 22, 2024In this episode featuring faculty from the United States and Europe, Aadia I. Rana, MD, and Laurence Slama, MD, PhD, discuss the subtleties of deciding among HIV treatment options in people with adherence challenges.
Listen as they debate the potential risks and benefits of long-acting ART in this population, considerations for people with viremia or resistance, recommendations concerning proviral DNA genotyping, and how to interpret guidelines and provide truly patient-centered care.
Presenters
Aadia I. Rana, MD
Professor of Medicine
Division of Infectious Diseases
University of Alabama at Birmingham Heersink School o...
Optimizing ART With Novel HIV Agents
Aug 16, 2024In this episode, Gregory Huhn, MD, MPHTM, presents a case study of a person with a long HIV treatment history, exploring when and how to consider agents with novel mechanisms of action.
Listen as he discusses:
The importance of engaging with patients to understand their perspectives and improve their satisfaction with their HIV careOptions in people with multiclass resistanceStudies of agents with novel mechanisms of action:BRIGHTE (fostemsavir)TMB-301/-311 (ibalizumab)CAPELLA (lenacapavir)Faculty
Gregory Huhn, MD, MPHTM,
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook...
Making Space for HIV Care: Starting in Care
Aug 16, 2024In this episode, Yvonne Gilleece, MB BCh, BAO, FRCP, uses a case study to illustrate why giving people space and time to engage in HIV care on their terms is key to overcoming potential shame and stigma.
She discusses how people can be very vulnerable when engaging in HIV care, and trauma-informed care can help address these vulnerabilities in a safe, respectful way. Listen as she gives her perspectives on:
Trauma-informed careOvercoming stigma and shameStaying in carePresenter:
Yvonne Gilleece, MB BCh, BAO, FRCP
Honorary Clinical Professor and Consultant in HIV Medicine & Se...
Keeping Up With HBV Care: Sharing Session 4
Aug 15, 2024In this episode, George Lau, MD, FRCP (Edin, Lond), FHKAM (Med), FHKCP, FAASLD, MBBS (HKU), and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Consequences to poor adherence to antiviral therapyStrategies to promote medication adherence (eg, patient education, setting up routines)The role of routine monitoring to prevent complications related to HBV such as hepatocellular carcinomaPresenter:
George Lau, MD, FRCP (Edin, Lond), FHKAM (Med), FHKCP, FAASLD, MBBS (HKU)
Specialist in Gastroenterology & Hepatology
Chairman and Senior Consultant in Gastroenterology and Hepatology
Humanity and Heal...
Optimizing Oral ART
Aug 14, 2024In this episode, Gregory Huhn, MD, presents a case study exploring how to optimize oral ART for a person with a long history of different ART regimens.
Listen as he discusses:
Reasons to consider regimen optimization in the setting of viral suppressionEvidence for INSTIs in the setting of resistanceData on when 2-drug regimens and long-acting regimens may or may not be good options
Faculty
Gregory Huhn, MD
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CO...
Beyond Viral Suppression—Pharmacist Perspectives
Aug 09, 2024In this episode, Lucas Hill, PharmD, AAHIVP, BCACP, and Bernadette Jakeman, PharmD, PhC, BCPS, AAHIVP,discuss what pharmacists need to know to provide high-quality HIV care beyond viral suppression, including treatment strategies and tips for addressing and improving patients’ quality of life.
Listen as they discuss:
Reasons to consider regimen optimization in the setting of viral suppressionEvidence that LA ART may reduce internalized stigmaDHHS recommendations on proviral DNA genotyping
Faculty
Lucas Hill, PharmD, AAHIVP, BCACP
HIV Pharmacist Specialist
UC San Diego Owen Clinic
Assistant Clinical Professor
UC San Diego Skag...
Optimizing PBC Pruritus Care in the Clinic
Jul 29, 2024In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss strategies for optimizing PBC pruritus care in the clinic setting.
Listen to their conversation on how important it is to ask patients about their pruritus, validate their symptoms and feelings, and offer treatment options framed with realistic expectations.
Presenters:
Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, Michigan
Marlyn J. Ma...
Duration: 00:21:06The Patient Experience With Cholestatic Pruritus in PBC
Jul 29, 2024In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss the patient experience with cholestatic pruritus in PBC.
Listen to their conversation on how people describe the experience of cholestatic pruritus, the extent to which pruritus negatively affects quality of life, and the importance of educating healthcare professionals on this important symptom of PBC.
Presenters:
Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
De...
How to Make Depression Care an Integral Part of HIV Care
Jul 24, 2024In this episode, Bradley N. Gaynes, MD, MPH, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating depression in people living with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, including creation of a virtual network and employment of measurement-based care.
Presenters:
Bradley N. Gaynes, MD, MPH
Ray M. Hayworth, MD and Family Distinguished Professor
Professor of Psychiatry and Epidemiology
Director, Division of Global Mental Health
Co-Director, Physician Scientist Training Program
Department of Psychiatry
University of North...
Managing Weight Gain on ART
Jun 27, 2024In this episode, Cristina Mussini, MD,and William R. Short, MD, MPH, FIDSA,discuss the potential role of ART in weight change among people living with HIV.
Listen to their conversation on whether ART switch can lead to weight loss after weight gain and how to counsel people living with HIV on weight loss options, including lifestyle modifications and nonpharmacologic methods.
Presenters
Cristina Mussini, MD
Director of Infectious Diseases Clinics
Professor of Infectious Diseases
University of Modena School of Medicine
Modena, Italy
William R. Short, MD, MPH, FIDSA
A Triumphant Return: Welcoming People Back to HIV Care
Jun 17, 2024In this episode, Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD, uses a case study to illustrate why patients living with HIV may disengage with their care and how best to reengage them once they present at the clinic, including discussion of:
The valid reasons patients have for disengaging with their HIV careWhy the return to care should be celebratedHow to support people living with HIV as they reengage in careHow to prevent future loss to follow-upPresenter:
Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD
CEO, Desmond Tutu Health Foundation
Director...
Mpox: Making Vaccination Routine
Jun 14, 2024In this second podcast of our series, hear expert faculty explore the CDC recommendations for mpox protection and discuss how vaccination can lead to immunologic equity. Topics include:
Should we consider mpox an STI?What strategies can be used to improve mpox vaccination and overcome the challenges of vaccine implementation?Can mpox vaccine be coadministered with other vaccines?What is the intersection between mpox and HIV?
Presenters
Carlos del Rio, MD
Distinguished Professor of Medicine (Infectious Diseases)
Emory University School of Medicine
Professor of Global Health and Epidemiology
Rollins School o...
Mpox Infection and Prevention
Jun 14, 2024Hear expert faculty answer common questions about the risk, impact, and recommendations for protection against mpox, including:
Why is mpox relevant to clinical practice?Who is at highest risk for mpox?How is mpox transmitted, and what are the clinical manifestations and complications of mpox infections?What are current ACIP recommendations for mpox vaccination?What about pre- and postexposure vaccination?
Presenters
Carlos del Rio, MD
Distinguished Professor of Medicine (Infectious Diseases)
Emory University School of Medicine
Professor of Global Health and Epidemiology
Rollins School of Public Health
Atlanta, Georgia
Duration: 00:19:41
Breaking Down Key PrEP Barriers: Patient and Regimen-Based Factors
May 31, 2024In this episode, Roger Bedimo, MD, MS, FACP, examines patient and regimen-based PrEP barriers and discusses practical interventions to support PrEP adherence in key populations. Topics covered include:
Individual and community perspectives on PrEP barriersKey barriers by principal populationsStrategies to support PrEP deliveryPrEP options for key populationsPrEP efficacy based on adherence in cisgender men and womenComparing FTC/TDF vs FTC/TAF or CAB for PrEPPrEP in pregnancy and breastfeedingDrug–drug interactions with gender-affirming hormone therapyPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Med...
Actively Countering Health Disparities to Improve PrEP Uptake
May 31, 2024In this episode, Roger Bedimo, MD, MS, FACP, discusses strategies to overcome health disparities to improve PrEP uptake, including:
Targeting key populations that would benefit from PrEP but have low rates of uptake, such as transgender women and people who inject drugsAddressing intersectionalityOvercoming implicit biasAddressing PrEP inequity by geographic regionExpanding PrEP uptake by expanding HCPs who prescribe itImproving PrEP education for both patients and HCPsPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas...
Addressing Provider and Structural PrEP Barriers
May 31, 2024In this episode, Roger Bedimo, MD, MS, FACP, examines provider-based and structural PrEP barriers and discusses practical methods for healthcare professionals to overcome these challenges. Topics covered include:
Potential provider barriers to prescribing PrEPStrategies to facilitate conversations about PrEPAddressing the gap in PrEP provider trainingStructural barriers for PrEP coverage, such as lack of insurance and complexity of billingInformed consent for minorsCDC guidelines on HIV testing and renal or lipid monitoring while on PrEPThe role of PrEP champions or PrEP navigators, such as in the SNAPS PrEP Navigation ProgramSolutions to common problems with PrEP persistence, such as use of t... Duration: 00:14:40Proactively Considering if Each Person Is on the Right HIV ART Regimen for Them
May 16, 2024In this episode, Tristan J. Barber, MA, MD, FRCP, and Roger Bedimo, MD, MS, FACP, help you decide whether and how to modify ART in virologically suppressed individuals by critically appraising whether using newer agents may improve their treatment satisfaction.
Listen to their conversation about their own approaches to evaluating whether each person living with HIV is taking the best ART regimen for them, as well as ways to proactively assess challenges people may be facing with their HIV ART.
Presenters
Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Royal...
HIV Monitoring for People Receiving Long Acting PrEP
May 10, 2024In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the updated CDC guidance on how to monitor for HIV in people receiving PrEP, including:
Rationale for why HIV monitoring differs for people receiving LA vs daily PrEPDescription of LEVI syndromeHow to transition a person from LA PrEP to HIV ART if they test positive for HIVPresenter:
Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier, Jr., MD Education Director and Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Medical Director
Care Point Health a...
Studies of LA ART in People With Adherence Challenges or Viremia
May 10, 2024In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the newest data supporting LA ART use in people with adherence challenges or viremia, including:
The LATITUDE study, an open-label phase III study of LA CAB + RPV in people with a suboptimal response or nonadherence to oral ARTUpdates to the Ward 86 cohort, which showed 81% of patients with viral suppression on LA CAB + RPV at Week 48The CARES study, an open-label, noninferiority phase IIIb study of LA CAB + RPV in people with baseline resistance mutationsPresenter:
Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier, Jr., MD...
Simplifying RSV Vaccination: Expert Q&A
May 08, 2024In this episode, Angela Branche, MD, FIDSA, and Jewel Mullen, MD, MPH, MPA, FACP, address commonly asked questions about the RSV vaccine, including:
Considerations for vaccine eligibilityRecommendations for pregnant personsVaccine administration based on RSV seasonalityUse of the vaccine in persons receiving immunosuppressive medicationsSafety data (eg, risk of serious adverse events)Natural immunity of RSVVaccine cost and insurance coverageFaculty:
Angela Branche, MD, FIDSA
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York
Jewel Mullen, MD, MPH, MPA, FACP
Associate De...
Implementing RSV Vaccines Into Practice
May 07, 2024In this episode, Jewel Mullen, MD, MPH, MPA, FACP, discusses strategies for implementing RSV vaccines into practice, with an emphasis on:
Understanding the reasoning for Advisory Committee on Immunization Practices RSV vaccine recommendations Factors that influence vaccine uptake and patient decision-makingConsiderations for patient and healthcare professional vaccine hesitancy Building vaccine confidence in both patients and healthcare professionalsUsing shared decision-making models (eg, SHARE approach)Faculty:
Jewel Mullen, MD, MPH, MPA, FACP
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Au...
Understanding Risk Factors for Severe RSV Disease
May 07, 2024In this episode, Angela Branche, MD, FIDSA, explores the burden of RSV disease in older adults, including:
RSV seasonality and disease burdenSymptoms and complications of RSV infectionOlder age as a key risk factor for severe RSV disease and complications (eg, pneumonia, hospitalization)Comorbidities associated with increased risk of RSV hospitalizationRSV hospitalization rates among different racial and ethnic minority groups and socioeconomic statusesFaculty:
Angela Branche, MD, FIDSA
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York
Content based on a CME p...
Duration: 00:14:06Optimizing Shingles Vaccine Uptake
Apr 30, 2024Using common case scenarios, Robert H. Hopkins, Jr., MD, MACP, and Laura P. Hurley, MD, MPH, discuss strategies for optimizing shingles vaccine uptake, including:
The pathophysiology of shingles to better understand risk and burdenCDC guidelines and ACIP shingles vaccine recommendations, including considerations for those who are immunocompromised Strategies for optimizing shingles vaccine uptake no matter the clinical settingHow to address shingles vaccine‒related adverse events Addressing insurance-related concernsPresenters:
Robert H. Hopkins, Jr., MD, MACP
Professor of Internal Medicine and Pediatrics
Chief, Division of General Internal Medicine
University of Arkansas for Medical Scien...
Integrating New Data From CROI 2024: Pharmacist Perspectives
Apr 29, 2024In this episode, Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, and Nimish Patel, PharmD, PhD, AAHIVP, cover the most impactful clinical studies presented at CROI 2024, including:
New data on long-acting ART, including:The CARES study of LA CAB + RPV in a sub-Saharan African population using a public health approachThe IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIVThe ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ARTUpdated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baselineCase series of LA... Duration: 00:27:52How Primary Care Providers Can Expand Their Role in HBV Management
Apr 26, 2024In this episode, learn how early and sustained HBV care can be enhanced by expanding the role of primary care providers in HBV management. Learn how to:
Engage key stakeholders in the provision of HBV careProvide HBV management resources to support PCPs who are doing screeningConsider specialty and primary care collaborations that empower PCPs with clear guidance on how to manage patients living with HBVPresenters:
Su Wang, MD, MPH, FACP
Medical Director
Center for Asian Health and Viral Hepatitis Programs
Cooperman Barnabas Medical Center
RWJBarnabas-Rutgers Medical Group
Associ...
Beyond Viral Suppression: A Case Study Addressing Internalized HIV Stigma
Apr 11, 2024In this episode, Gregory Huhn, MD, MPHTM, uses a case study to explore the reasons healthcare professionals and people living with HIV may want to further optimize ART in the setting of viral suppression.
To determine the best outcome for this case study, Dr Huhn discusses the reasons individuals may not be satisfied with daily oral ART and examines data to suggest that, for some individuals with virologic suppression, switching to long-acting ART may address internalized HIV stigma.
Finally, Dr Huhn takes a look at the optimal candidates for switching to a long-acting ART regimen a...
Duration: 00:12:29Linkage to Care After HBV Diagnosis: Sharing Session 3
Apr 10, 2024In this episode, Maria Buti, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Barriers to HBV screening, including patient- and provider-specific barriers (eg, lack of education, failure to disclose or discuss risk factors, perceived low risk, stigma)Applying CDC recommendations for universal HBV screening in adults Strategies to improve HBV transitions of care (eg, improved education, simplify criteria for screening and monitoring, alternative testing sites)Importance of testing close contacts for HBV after initial diagnosis and promoting HBV vaccination
Presenter:
Maria Buti, MD
Key HIV Studies From CROI 2024 Influencing Clinical Practice
Mar 29, 2024In this episode, Joseph J. Eron, Jr., MD, and Monica Gandhi, MD, MPH, discuss the key HIV studies from CROI 2024 that are influencing their clinical practice, including:
New data surrounding long-acting ART, including:The CARES study of LA CAB + RPV in a Sub-Saharan African population using a public health approachThe IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIVThe ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ARTUpdated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baselineCase se... Duration: 00:44:22How to Implement Earlier Hepatitis B Treatment
Mar 26, 2024In this episode, Mark S. Sulkowski, MD, FIDSA, FAASLD; Tatyana Kushner, MD, MSCE; Paul Y. Kwo, MD; and patient advocate Jacki Chen, PhD, consider barriers and solutions for more expansive HBV treatment in the United States. Topics include:
Patient subgroups to consider for treatment outside guideline criteriaAdverse event and cost-effectiveness considerationsIntegration of patient perspectives in wider treatmentPresenters:
Mark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases, Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, Maryland
Tatyana Kushner, MD, MSCE
Empowering Patients With Education on HBV: Sharing Session 2
Mar 11, 2024In this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Opportunities to improve patient education, including education for expectant mothers with HBVPotential cultural considerations that may result in delayed HBV diagnosis and care Stigma reduction with universal HBV screening and vaccinationStrategies to improve patient education (eg, online resources, advocacy groups, use of layman’s terms and diagrams, repetition)Presenter:
Robert Wong, MD, MS
Clinical Associate Professor
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto...
Switching HIV ART in Older People With Weight Gain and Cardiovascular Comorbidities
Mar 08, 2024Listen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including:
Polypharmacy and deprescribingThe risk of cardiovascular events with various ART regimensApproaches for managing weight gainPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, Texas
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Duration: 00:14:42Optimizing ART in Priority Populations: Initiating ART in Transgender Women
Mar 04, 2024In this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including:
Providing services in a gender-affirmative care modelProactive counseling on drug-drug interactions with gender-affirming hormone therapyStrategies to reduce adverse eventsPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, Texas
Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, G...
Duration: 00:12:29COVID-19 Case Challenges: Employing Outpatient Antivirals and Addressing Drug‒Drug Interactions
Feb 27, 2024In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes:
Current COVID-19 landscapeCOVID-19 testing and vaccination recommendationsTreatment guidelines and antiviral options for nonhospitalized adults with COVID-19Resources for assessing and managing COVID-19 antiviral-related drug-drug interactionsAnswers to learners’ most pressing questionsPresenters:
Renslow Sherer, MD
Professor of Medicine
Section of Infectious Diseases and Global Health
University of Chicago
Chicago, Illinois
Trinh P. V...
Duration: 00:34:26New Audio Updates: CCO Independent Conference Coverage of Hepatitis B at AASLD 2023
Feb 05, 2024In this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including:
Current therapiesStudies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDFKaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis BEarly vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV TransmissionInvestigational functional cure strategiesB-Together: Sequential Bepirovirsen and PegIFN Added to NA Therapy for Chronic HBV InfectionMARCH Part B: VIR-3434 ± VIR-2218 ± PegIFN Added to NA Therapy for Chronic HBV InfectionREEF-IT: JNJ-3989 + NA ± JNJ-6379 With PegIFN Add-on Consolidation in Patients With HBe... Duration: 00:37:12Reconsidering Your Approach: Strategies to Support PrEP Persistence and Reengagement
Jan 31, 2024In this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including:
Racial disparities in the PrEP care continuumConsideration that PrEP persistence may be less about relationship to the drug than the environmentExamples of HCP implicit bias regarding PrEP responsibility based on racism and sexual prejudiceImpact of HCP implicit bias on PrEP persistenceImpact of racism on clinical cognitionThe demonstrated effects of stereotype threat and the potential he... Duration: 00:27:00My Journey With HBV and HDV: Sharing Session 1
Jan 24, 2024In this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including:
The importance of patient education along the care continuumEnsuring smooth transitions of care and communication between medical teamsScreening hepatitis delta in persons with chronic hepatitis BManaging hepatitis delta, including considerations for clinical trialsPromoting patient advocacyPresenter:
Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois
Why I Started and Why I Stayed on HIV PrEP
Jan 12, 2024In this episode, David Saunders discusses the value of nonstigmatizing discussions between people using HIV pre-exposure prophylaxis (PrEP) and healthcare professionals, including:
Encouraging accountability to individualize adherence strategies and improve persistence to PrEPReducing stigma, discrimination, and prejudice in healthcare settings to foster PrEP persistence
Faculty:
David Saunders
PrEP User and Advocate
Link to full program:
https://bit.ly/3ZlICsL
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Duration: 00:06:15Long-Acting PrEP: Strategies to Support PrEP Persistence and Reengagement
Jan 10, 2024In this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including:
The PrEP care continuum for adolescentsSystem barriers to PrEP coverage and privacy concerns for adolescentsThe benefits and challenges of same-day PrEP initiation and real-world data to support itInterventions to support PrEP persistencePrEP options for different populations and the data to support the efficacy of long-acting cabotegravir (CAB) PrEP from HPTN 083 and HPTN 084Data and recommendations for a CAB PrEP oral lead-inData from HPTN 083 showing no interaction between feminizing hormone t... Duration: 00:29:38